In episode #106 Troy shares his expertise as the founder of a pharmaceutical company and his personal story experiencing infertility with his wife. Troy has always been interested in health research, and he discovered the MTHFR mutation issue in 2010. He began a deep dive into this issue as it relates to fertility and pregnancy, and he was amazed by how many people are affected. With the right tests, it was discovered that his wife had the MTHFR mutation. Proper supplementation allowed her to get pregnant and they were able to have their second child. We discuss the difference between folic acid and folate, how the MTHFR mutation affects fertility and pregnancy, and how proper folate supplementation can make a big difference. References are listed below, and Troy is offering a discount code for your first bottle of prenatal vitamins from his company, Centurion Labs. Topics Discussed: infertility, folic acid, folate, MTHFR mutation, prenatal vitamins CONNECT WITH TROY - centurionlabs.com Use coupon code HOPE for 67% off your first bottle of prenatal vitamins! MISCARRIAGE HOPE DESK RESOURCES- Miscarriage Hope Desk aims to help women struggling miscarriage, pregnancy loss and recurrent miscarriages (RPL), by providing the following resources- - Library of Articles, found here- https://miscarriagehopedesk.com/library/understanding-why/ - Instagram Community- https://instagram.com/miscarriagehopedesk - Facebook Community- https://www.facebook.com/groups/1617075958466247/ - Free Miscarriage Lab Checklist- https://miscarriagehopedesk.com/labs - Free Weekly Newsletter- http://miscarriagehopedesk.com/newsletter FREE MEAL PLANS Do you need help getting healthy, tasty meals on the table? Check out our sponsor Prep Dish, PrepDish.com/mhd to get 2 weeks FREE! SHOW NOTES- https://miscarriagehopedesk.com/podcast/ Get a FREE Miscarriage Lab Testing Checklist- MiscarriageHopeDesk.com/labs REFERENCES: Scaglione, F., Panzavolta, G., Folate, Folic Acid and 5-methyltetrahydrofolate are not the same thing, Xenobiotica. Feb. 2014 Servy, Edouard, et.al., MTHFR isoform carriers. 5-MTHF (5-methyl tetrahydrofolate) vs. folic acid: a key to pregnancy outcome: a case series. Journal of Assisted Reproduction and Genetics. https://doi.org/10.1007/s10815-018-1225-2 Greenberg, J. Multivitamin Supplementation During Pregnancy: Emphasis on Folic Acid and L-Methylfolate. Reviews in Obstetrics & Gynecology. 2011, Vol. 4 pg 126-127. D’Elia, PQ., et.al., MTHFR polymorphisms C677T and A1298C and associations with IVF outcomes in Brazilian women. Reproductive Biomedicine Online 2014 Jun;28(6):733-8. doi: 10.1016/j.rbmo.2014.02.005. Naqvi, H., et.al., Role of 677C® T polymorphisms a single substitution in methylenetetrahydrofolate reductase (MTHFR) gene in North Indian infertile men. Molecular Biology Reports. Feb. 2014; 41(2):573-9. Mfady, DS, et. al., Associations of variants in MTHFR and MTRR genes with male infertility in the Jordanian population. Gene. 2014 Feb 15;536(1):40-4. doi: 10.1016/j.gene.2013.12.001. Gava, MM, et.al., Polymorphisms in folate-related enzyme genes in idiopathic infertile Brazilian men. Reproductive Sciences 2011 Dec;18(12):1267-72. doi: 10.1177/1933719111411729. Shen, O., et.al., Association of the Methylenetetrahydrofolate Reductase Gene A1298C Polymorphism with Male Infertility: A Meta-Analysis Updated Estimates of Neural Tube Defects Prevented by Mandatory Folic Acid Fortification, Centers for Disease Control (CDC): Morbidity and Mortality Weekly Report (MMWR), January 16, 2015. McGowan, E., et.al., Association Between Folate Metabolites and the Development of Food Allergy in Children. Journal of Allergy and Clinical Immunology. January 2020; 8(1):132-140. McStay, Catrina, Maternal Folic Acid Supplementation during Pregnancy and Childhood Allergic Disease Outcomes: A Question of Timing. Nutrients. 2017 February. Wang, T., et. al., Is Folate Status a Risk Factor for Asthma or Other Allergic Diseases?, Allergy, Asthma & Immunology Resea