The National Asthma Education and Prevention Program (NAEPP) of the NIH has updated its guideline recommendations for diagnosis and treatment of asthma patients. Michelle M. Cloutier, MD, from UConn Health, Stephanie Lovinsky-Desir, MD, of Columbia University Irving Medical Center, and JAMA Associate Editor George O'Connor, MD, MS, from Boston Medical Center join JAMA's Q&A series to discuss what's new, including revised advice about • Use of intermittent inhaled corticosteroids (ICSs) • Use of add-on long-acting muscarinic antagonists (LAMAs) • Use of fractional exhaled nitric oxide (FeNO) measurement as a diagnostic biomarker • Monitoring response to therapy • Indoor allergen mitigation strategies • Safety and efficacy of subcutaneous and sublingual immunotherapy • Use of bronchial thermoplasty Recorded December 8, 2020 Related Article(s): Managing Asthma in Adolescents and Adults