18 min listen
The immune system, CAR-T therapy and cancer
FromSteministas
ratings:
Length:
18 minutes
Released:
Apr 21, 2020
Format:
Podcast episode
Description
The immune system has become a hot topic recently with COVID-19's spread but did you know that scientists can manipulate the immune system to fight cancer? In this episode we go over the basics of the immune system, discuss how cancer can hijack the immune system and introduce you to CAR-T therapy!
// SOURCES
Types of T-cells: https://www.celiackidsconnection.org/2018/05/06/what-are-the-different-types-of-t-cells/
Great summary of the nature article: https://www.sciencealert.com/new-t-cell-therapy-kills-most-human-cancer-types-and-might-work-across-individuals
Hallmarks of cancer: https://blogs.scientificamerican.com/guest-blog/the-hallmarks-of-cancer-9-reprogramming-energy-metabolism/
Journal article on glycolysis and immune system: https://www.cell.com/cell-metabolism/pdf/S1550-4131(18)30178-5.pdf
Personalis article: https://www.personalis.com/understanding-role-human-leukocyte-antigen-cancer-immunotherapy/
What is CAR-T therapy: https://www.cartcellscience.com/car-t-cell-therapy-frequently-asked-questions/
Lymphoma CAR-T: https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(17)30058-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1525001617300588%3Fshowall%3Dtrue#secsectitle0020
// SOURCES
Types of T-cells: https://www.celiackidsconnection.org/2018/05/06/what-are-the-different-types-of-t-cells/
Great summary of the nature article: https://www.sciencealert.com/new-t-cell-therapy-kills-most-human-cancer-types-and-might-work-across-individuals
Hallmarks of cancer: https://blogs.scientificamerican.com/guest-blog/the-hallmarks-of-cancer-9-reprogramming-energy-metabolism/
Journal article on glycolysis and immune system: https://www.cell.com/cell-metabolism/pdf/S1550-4131(18)30178-5.pdf
Personalis article: https://www.personalis.com/understanding-role-human-leukocyte-antigen-cancer-immunotherapy/
What is CAR-T therapy: https://www.cartcellscience.com/car-t-cell-therapy-frequently-asked-questions/
Lymphoma CAR-T: https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(17)30058-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1525001617300588%3Fshowall%3Dtrue#secsectitle0020
Released:
Apr 21, 2020
Format:
Podcast episode
Titles in the series (48)
Does Vitamin D prevent the flu?: With flu season upon us everyone is trying to figure out ways to avoid getting the flu. Recently, Vitamin D has been suggested to prevent the flu more than the flu shot. In this video we dive into this claim and investigate some primary literature to det... by Steministas