Discussing new guidelines on the use of vancomycin for severe Staphylocccus aureus infections. The August issue of AAC includes interesting papers about mechanism of resistance to metronidazole in C. difficile, a variant of KPC resistant to ceftazidime-avibactam and description of a new “ultra-broad spectrum B-lactamase inhibitor” among others! You can find the issue at https://aac.asm.org.