This audio program discusses psychiatric complications of medical marijuana; linkage of depression to a region on chromosome 3; cognitive effects of antipsychotics in demented patients; the relationship of schizophrenia to Toxoplasma gondii and to herpes simplex, type 1; the relationship between cognition and functioning in young people at high risk for psychosis; and outcomes of young people at high risk for psychosis who do not become psychotic. Articles can be viewed online at www.ajp.psychiatryonline.org.