Atlas of Lymphatic System in Cancer: Sentinel Lymph Node, Lymphangiogenesis and Neolymphogenesis
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About this ebook
This atlas contains a large number of original photographs illustrating the anatomy, research methods, and structural features of the structure of the lymphatic apparatus in oncological diseases. The tissue complexes of the axillary region have been studied in detail. The lymphatic maps of the axillary region in cancer are presented, including those with manifestations of lymphangiogenesis; newly formed lymph nodes formed as a result of neolymphogenesis are also considered. Atlas of Lymphatic System in Cancer: Sentinel Lymph Node, Lymphangiogenesis and Neolymphogenesis is intended for oncologists, anatomists, morphologists and doctors of other specialties. The book is the result of ten years of research. The applied technology of ultrasonic isolation of anatomical structures made it possible to take a fresh look at the lymphatic apparatus in cancer and describe the phenomenon of neolymphogenesis.
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Atlas of Lymphatic System in Cancer - Shamil Gantsev
Shamil Gantsev, Kamil Gantsev and Shamil Kzyrgalin
Atlas of Lymphatic System in Cancer
Sentinel Lymph Node, Lymphangiogenesis and Neolymphogenesis
../images/490938_1_En_BookFrontmatter_Figa_HTML.pngShamil Gantsev
Oncology Chair, Bashkir State Medical University, Ufa, Russia
Kamil Gantsev
Oncology Chair, Bashkir State Medical University, Ufa, Russia
Shamil Kzyrgalin
Oncology Chair, Bashkir State Medical University, Ufa, Russia
ISBN 978-3-030-40966-1e-ISBN 978-3-030-40967-8
https://doi.org/10.1007/978-3-030-40967-8
© Springer Nature Switzerland AG 2020
This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.
The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use.
The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, expressed or implied, with respect to the material contained herein or for any errors or omissions that may have been made. The publisher remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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Abstract
The study of the primary tumor has always been dominant in the planning of basic and clinical studies in oncology. In recent years, there has been a clear shift in scientific interests towards the study of the metastatic properties of cancer cells. Despite the large number of studies in the field of metastatic processes, there are many unresolved issues.
Typically, the circulatory and lymphatic systems are involved in metastasis. However, the lymphatic system is most often the primary focus of metastasis. Indeed, in many cases, the detection of tumor metastases in regional lymph nodes is the first step in the spread of the tumor, as well as one of the most important prognostic markers for the patient.
Historically, lymphatic vessels have been considered passive participants in the process of metastasis, providing only the transit of tumor cells to the lymph nodes. The discovery of several key specific lymphatic molecular markers and the increased availability of in vivo and in vitro experimental systems for the study of lymphatic function have provided a much more complex and active role in tumor metastasis.
This atlas contains a large number of original figures illustrating the anatomy, research methods, and structural features of the lymphatic apparatus in cancer. Shown are lymphatic maps of the axillary region in cancer, including those with manifestations of neolymphangiogenesis; newly formed lymph nodes formed as a result of neolymphogenesis.
It is intended for oncologists, surgeons, anatomists, morphologists, and doctors of other specialties. It is the result of 10 years of research. The applied technology of ultrasonic isolation of anatomical structures made it possible to take a fresh look at the lymphatic apparatus in cancer and to discover the previously not described phenomenon of neolymphogenesis. We hope that this publication will help advance in understanding the logistics of metastasis.
Reviews
../images/490938_1_En_BookFrontmatter_Figh_HTML.pngThe publication,Atlas of Lymphatic System in Cancer: Sentinel Lymph Node, Lymphangiogenesis, and Neolymphogenesis , by Shamil Gantsev, Kamil Gantsev, and Shamil Kzyrgalin represents a generously illustrated catalogue of the role of the lymphatic system in cancer metastasis. I consider this work novel and clinically relevant for understanding the complex processes involved in tumor cell spread through the lymphatic system. The authors describe the change from considering the lymphatic vessels and the lymph nodes as passive structures
in the transit of spreading tumor cells to a complex system which actually plays an active role
in the process of tumor metastasis. The atlas contains seven well-written and well-illustrated chapters (including introduction and conclusion); among those chapters, novel and clinically important aspects are particularly discussed in Chapter 2 (Lymph Nodes in Cancer: Sentinel Lymph Node
) and Chapter 5 (Neolymphogenesis
). As – to my opinion – there is no comparable work so far in the published literature, I highly recommend this publication. The insights from this work will help promote further research – both morphologically and on the molecular level – to better understand the meaning and processes in tumor cell spread through the lymphatic system.
Professor Christopher Poremba
Director, Institute of Pathology Munich, Nord
Institute of Molecular Pathology Bavaria