Neuroanatomy Notes
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About this ebook
This book is designed to enhance understanding of neuroanatomy and eliminate neurophobia which is not uncommon among medical and healthcare students. The intrinsic complex nature of the subject has been simplified using mnemonics and diagrams with crammable informations in bullets along with their clinical implications.
Key features:
- Covers clinically and academically important topics
- Schematic diagrams
- Visual mnemonics
- Useful for medical students, PG and USMLE aspirants
Chapters:
- How to draw mid-brain cross-section?
- How to draw pons cross-section?
- How to draw medulla cross-section?
- Spinal cord cross-section and tracts simplified
- Vertebro-basilar arterial systems and syndromes
- Circle of willis - mnemonics and drawing
- Circle of willis and blood supply of forebrain
- Dural reflections and venous sinuses
- Microanatomy of cerebral cortex
- Brodmann areas and lesions
- Thalamic connections
- Nuclei of hypothalamus
- Internal capsule
- Simplified basal ganglia
- CSF circulation
- Trigeminal nerve
- Facial nerve
- Auditory pathway and Vestibular pathway
- 10 retinal layers
- Visual pathway
- Horizontal conjugate gaze pathway
- Limbic system
- Brown-sequard syndrome - Anatomical basis
- Lateral medullary syndrome (Wallenberg syndrome) - Anatomical basis
- Medial medullary syndrome (Djerine syndrome) - Anatomical basis
- Brachial plexus
- Lumbar plexus
Dr. Sulabh Kumar Shrestha
I'm Dr. Sulabh Kumar Shrestha, currently undertaking residency in Orthopedics. The allure of beautiful benign darkness makes me write sometimes. I'm fascinated by the mysteries of life and death and everything in between. I like to write in rhymes and even force it at times. Writing gives me a little escape.
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Neuroanatomy Notes - Dr. Sulabh Kumar Shrestha
How to Draw Pons Cross-Section?
The cross-section of pons is similar to the midbrain as described earlier but few things must be kept in mind:
The orientation of lemnisci in midbrain is more or less vertical, but in pons it is horizontal.
Cranial nerve III and IV arises from midbrain and mainly Cranial nerve V, VI, VIII and VIII arises from pons.
Cerebral aqueduct lies in midbrain and 4th ventricle lies in pons.
We will use the analogy of an "inverted face of a human" to draw the cross-section of pons.
pons mnemonicNow, let’s label the structures shown above:
Hair = Transverse pontine fibers
Eye = Corticospinal and Corticonuclear tracts
Ear = Middle cerebellar peduncle
Stripes = Lemnisci
Medially: Medial lemniscus
Middle: Trigeminal lemniscus medially and Spinal lemniscus laterally
Lateral: Lateral lemniscus
Bridge of nose = Raphe nucleii
Ala of nose = Medial Longitudinal Fasciculus
Mole = Facial nerve motor nucleus (In caudal pons)
Moustache = Cranial nerve nucleii
Medial most = CN VI or Abducens nerve (In caudal pons)
Middle = CN V or Trigeminal nerve – motor and sensory (In rostral pons)
Lateral most = CN VIII – Superior vestibular nucleus (In rostral pons)
Lips = Periventricular gray
Contains locus coeruleus
Open mouth = 4th ventricle
Chin = Superior cerebellar peduncle
Now, let’s look at the real picture:
pons cross-sectionHow to Draw Medulla Oblongata Cross-section?
Like in Midbrain and Pons:
Corticospinal tract passes ventrally.
Ventricular system is dorsal in midline.
Cranial nerve nuclei are located just anterior to the ventricle.
Medial longitudinal fasciculus is present around the center.
Caudal medulla resembles "spinal cord":
Circular in shape
Central canal instead of 4th ventricle
Nucleus gracilis and nucleus cuneatus dorsally
Pyramids and medial lemnisci decussate
medulla drawingHow to draw medulla cross-section?
Draw a pair of circles
Inferior cerebellar peduncle
Draw another pair of circles anteriorly
Inferior olivary nucleus
Draw a triangle in the center between 2 posterior circles
4th ventricle
Draw a pair of triangles anterior to the 2 anterior circles
Pyramids
Draw a boomerang just anterior to the triangle representing 4th ventricle
Periventricular gray
Draw another boomerang anterior to the previous boomerang
Cranial nerve nucleii (from medial to lateral)
CN XII
Dorsal vagal nucleus
Nucleus tractus solitarius
Medial vestibular nucleus
Posterior cochlear nucleus
Draw a pair of rectangles in the center
Represents medial lemniscus (anteriorly) and Medial Longitudinal Fasciculus (MLF) posteriorly
Draw a pentagon with apex tilted medially, just anterior to the posterior pair of circles – the 5 points of the pentagon represents 5 structures (starting from apex in clockwise fashion)
Nucleus ambiguus
Trigeminal nerve nucleus and spinal tract
Anterior cochlear nucleus
Anterior spinocerebellar tract
Lateral spinocerebellar tract
Lateral spinothalamic tract inside the pentagon
Now, look how a real cross-section would look like:
https://upload.wikimedia.org/wikipedia/commons/9/94/Gray694.pnghttps://commons.wikimedia.org/wiki/File:Gray694.png
Henry Vandyke Carter [Public domain]
Spinal Cord Cross-section and Tracts Simplified
spinal tractsOrganization of Ascending and Descending Tracts in Spinal Cord
A. 2 Posterior Tracts:
The fibers of these tracts cross to the opposite side at the level of medulla:
Dorsal column (Cross at medulla)
Fasciculus gracilis
Fasciculus cuneatus
Lateral corticospinal tract (Cross at medulla)
B. 2 Lateral Tracts:
The fibers of these tracts remain on ipsilateral side:
Dorsal spinocerebellar tract (Do not cross)
Ventral spinocerebellar tract (Crosses 2 times to lie on ipsilateral side)
1st crossing in the spinal cord
2nd crossing in the cerebellum
C. 2 Anterior Tracts:
The fibers of these tracts cross at the level of spinal cord:
Anterior corticospinal tract
Anterior and Lateral spinothalamic tract
D. Extrapyramidal tracts:
Rubrospinal tract (Cross at midbrain)
Vestibulospinal tract: Uncrossed
Reticulospinal tract: Uncrossed
Olivospinal tract: Uncrossed
spinal tract somatotropyNow, look at the somatotropic arrangement of the various tracts:
Fasciculus gracilis:lower limbs
Fasciculus cuneatus:upper limbs
Corticospinal tract:upper limbs medially and lower limbs laterally
Spinothalamic tract:upper limbs medially and lower limbs laterall
Vertebrobasilar Arterial System and Syndromes
Vertebral Artery
Iuse the analogy of hand to remember the vertebral artery and its branches:
vertebral-artery-mnemonicIndex and ring fingers – Vertebral arteries of 2 sides; Middle finger – Anterior spinal artery; Thumb and pinky fingers – Posterior Inferior Cerebellar Artery (PICA) of 2 sides; Wrist – Pontomedullary junction where 2 vertebral arteries converge; Forearm – Basilar artery; Remember if there is anterior spinal artery, there is also posterior spinal artery (not shown here) which can arise wither from vertebral artery or PICA.
Origin: Branch of subclavian arteries
Course:
Ascends through transverse foramina on C6 through C1 and enters posterior fossa through foramen magnum
Continue up the ventral surface of medulla
Converge at the ponto-medullary junction to form single basilar artery
Branches are given inside cranial vault, once it has entered through foramen magnum
Supplies: Spinal cord, Medulla and Inferior cerebellum
Branches:
1. Anterior spinal artery (Single artery):
Run down the front of the spinal cord
Supplies ventrolateral 2/3rd of cervical spinal cord and ventrolateral medulla
2. Posterior spinal arteries:
Bilaterally run down dorsolateral to spinal cord
Supplies posterior 1/3rd of cervical spinal cord and posterior medulla
Clinical Correlate
1. 10 medullary arteries arising from segmental branches of aorta feeds anterior and posterior spinal artery along their course. In lower thoracic/upper lumbar region, large segmental artery exists and usually on Left