Immunotherapy drives mesenchymal shift in GBM

FromNeuro-Oncology: The Podcast

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Immunotherapy drives mesenchymal shift in GBM

FromNeuro-Oncology: The Podcast

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Length:

24 minutes

Released:

May 17, 2024

Format:

Podcast episode

Description

Dr. Maya Graham interviews Drs. Josephine Hendriksen and Joachim Weischenfeldt about their recent manuscript, "Immunotherapy drives mesenchymal tumour cell state shift and TME immune response in glioblastoma patients," published online in Neuro-Oncology in May 2024.

Released:

May 17, 2024

Format:

Podcast episode

Titles in the series (82)

Neuro-Oncology: The Podcast will keep you up to date about the latest advances in the field as we present conversations with the authors of selected papers from Neuro-Oncology and its sister journals, Neuro-Oncology Practice and Neuro-Oncology Advances.

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Immunosuppression in IDH mutant gliomas: Dr. Maya Graham interviews Dr. Nduka Amankulor about the recent manuscript entitled: "Characterization of systemic immunosuppression by IDH mutant glioma small extracellular vesicles" published online in Neuro-Oncology in July 2021. by Neuro-Oncology: The Podcast
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Resection for recurrent brain metastases: Dr. Iyad Alnahhas interviews Dr. Alexander Hulsbergen about his and his team's recent manuscript entitled: "Neurosurgical resection for locally recurrent brain metastases", published online in Neuro-Oncology in July 2021. by Neuro-Oncology: The Podcast
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Supratotal resection of lower-grade gliomas: Dr. Alireza Mansouri talks with Dr. Lorenzo Bello about his recently published article in Neuro-Oncology entitled: "Association of Supratotal Resection with Progression-Free Survival, Malignant Transformation, and Overall Survival in Lower-Grade... by Neuro-Oncology: The Podcast
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A subset of pediatric thalamic gliomas: Dr. Iyad Alnahhas talks with Dr. Felix Sahm about his recently published article in Neuro-Oncology entitled: "A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR,"... by Neuro-Oncology: The Podcast
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Epidemiology of Brainstem High-Grade Gliomas in Children and Adolescents in the United States, 2000-2017: Dr. Evan Noch interviews Dr. Jill Barnholtz-Sloan about her recent paper "Epidemiology of Brainstem High-Grade Gliomas in Children and Adolescents in the United States, 2000-2017" published online in Neuro-Oncology in December 2020. by Neuro-Oncology: The Podcast
17 min listen
A large longitudinal study of patients with Neurofibromatosis Type 2.: Dr. Iyad Alnahhas interviews Dr. Gareth Evans about his recent paper in Neuro-Oncology entitled: "Disease course of Neurofibromatosis Type 2; a 30-year follow-up study of 353 patients seen at a single institution by Neuro-Oncology: The Podcast
21 min listen
Molecular signatures of glioma causation: Dr. Evan Noch interviews Dr. Elizabeth Claus about her recent manuscript entitled: "Environmental and sex-specific molecular signatures of glioma causation" published online in Neuro-Oncology in May 2021. by Neuro-Oncology: The Podcast
22 min listen
Loss of H3K27me3 in meningiomas: Dr. Evan Noch interviews Drs. Farshad Nassiri and Justin Wang from the team of Dr. Gelareh Zadeh about their recently published paper entitled “Loss of H3K27me3 in meningiomas” published online in Neuro-Oncology in May 2021. by Neuro-Oncology: The Podcast
26 min listen
Cold-Inducible RNA-Binding Protein expression and recurrence of brain metastases: Dr. Alireza Mansouri interviews Dr. Matthew Dankner about his recent paper "Invasive growth associated with Cold-Inducible RNA-Binding Protein expression drives recurrence of surgically resected brain metastases" published online in Neuro-Oncology in... by Neuro-Oncology: The Podcast
11 min listen
Immunotherapy for melanoma brain metastases: Dr. Ankush Bhatia interviews Dr. Hussein Tawbi about his and his team's recent manuscript entitled "Safety and efficacy of the combination of nivolumab plus ipilimumab in patients with melanoma and asymptomatic or symptomatic brain... by Neuro-Oncology: The Podcast
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A prospective phase II randomized trial of proton radiotherapy vs intensity modulated radiotherapy for patients with newly diagnosed GBM: Dr. Jasmin Jo interviews Dr. Caroline Chung about her paper: “A prospective phase II randomized trial of proton radiotherapy vs intensity modulated radiotherapy for patients with newly diagnosed GBM” published online in Neuro-Oncology in Feb 2021. by Neuro-Oncology: The Podcast
14 min listen
A serum based DNA methylation assay to detect gliomas: Dr. Iyad Alnahhas interviews Dr. Houton Noushmehr about his recent paper "A serum-based DNA methylation assay provides accurate detection of glioma", published online in Feb 2021 in Neuro-Oncology by Neuro-Oncology: The Podcast
33 min listen
Trabectedin for recurrent grade 2 or 3 meningiomas: Dr. Iyad Alnahhas interviews Dr. Matthias Preusser about the recent manuscript entitled: "Trabectedin for recurrent WHO grade 2 or 3 meningioma: a randomized phase 2 study of the EORTC Brain Tumor Group (EORTC-1320-BTG)", published online in... by Neuro-Oncology: The Podcast
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Posterior fossa syndrome: Dr. Iyad Alnahhas interviews Dr. Raja Khan about their recent manuscript entitled "Clinical features, neurologic recovery, and risk factors of post-operative posterior fossa syndrome and delayed recovery: a prospective study", published online in... by Neuro-Oncology: The Podcast
22 min listen
PTEN deficiency and proteosome addiction in glioblastoma: Dr. Evan Noch interviews Drs. Frank Furnari and Jorge Benitez about their recent paper: "PTEN deficiency leads to proteosome addiction, a novel vulnerability in glioblastoma" published online in Neuro-Oncology in January, 2021. by Neuro-Oncology: The Podcast
23 min listen
Vorinostat and bevacizumab for recurrent glioblastoma: Dr. Iyad Alnahhas interviews Drs. Vinay Puduvalli and Ying Yuan about their paper "A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma" published in Neuro-Oncology... by Neuro-Oncology: The Podcast
33 min listen
The clinical utility of next generation sequencing for IDHwt glioblastoma: Dr. Evan Noch interviews Dr. Mary Jane Lim-Fat about her and her team's recent manuscript entitled: "Clinical utility of targeted next generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making", published online in... by Neuro-Oncology: The Podcast
22 min listen
Brain radiotherapy and decline in fine motor skills: Dr. Iyad Alnahhas interviews Dr. Jona Hattangadi-Gluth and Ms. Mia Salans about their recently published manuscript entitled: "Longitudinal change in fine motor skills after brain radiotherapy and in vivo imaging biomarkers associated with... by Neuro-Oncology: The Podcast
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EGFR: the lazarus target in glioblastom: Dr. Maya Graham interviews Drs. Benjamin Lin, David Nathanson, Frank Furnari and Ryan Miller about their recent manuscript entitled: "EGFR, the Lazarus target for precision oncology in glioblastoma", published online in Neuro-Oncology in September 2022. by Neuro-Oncology: The Podcast
38 min listen
The incidence of brain metastases among patients with metastatic breast cancer: Dr. Iyad Alnahhas interviews Dr. Katarzyna Jerzak about her recent paper “The incidence of brain metastases among patients with metastatic breast cancer: a systematic review and meta-analysis”, published online in Neuro-Oncology in December,... by Neuro-Oncology: The Podcast
24 min listen
Checkpoint blockade in atypical meningiomas: Description: Dr. Nicholas Butowski interviews Dr. David Reardon about his recent manuscript "Activity of PD-1 blockade with nivolumab among patients with recurrent atypical/anaplastic meningioma: phase II trial results", published online in... by Neuro-Oncology: The Podcast
40 min listen
Temozolomide-induced hypermutation in IDH-mutant low-grade gliomas: Dr. Maya Graham interviews Dr. Nancy Ann Oberheim Bush about her and her team's paper entitled " Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant... by Neuro-Oncology: The Podcast
13 min listen
18F FET PET in childhood CNS tumors: Description: Dr. Maya Graham interviews Dr. Lisbeth Marner about her recent manuscript "" Diagnostic accuracy and clinical impact of 18F FET PET in childhood CNS tumors" " published online in April 2021 in Neuro-Oncology. by Neuro-Oncology: The Podcast
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Loss of H3K27me3 in the Tübingen meningioma cohort: Dr. Maya Graham interviews Drs. Ghazaleh Tabatabai and Felix Behling about their paper entitled “H3K27me3 loss indicates an increased risk of recurrence in the Tübingen meningioma cohort” published online in Neuro-Oncology in December 2020. by Neuro-Oncology: The Podcast
18 min listen
Testing methods for MGMT promoter methylation: Dr. Iyad Alnahhas interviews Dr. Kathreena Kurian about her and her team's recent manuscript entitled: "MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis... by Neuro-Oncology: The Podcast
13 min listen
Clinical trial accrual for women and minorities in neuro-oncology: Dr. Rachna Malani interviews Dr. Hervey-Jumper about his and his team's recent manuscript entitled "", published online in Neuro-Oncology in January 2022. See study here by Neuro-Oncology: The Podcast
28 min listen
DNA methylation profiles within the CATNON trial: Dr. Iyad Alnahhas interviews Dr. Pim French about his and his team recent manuscript entitled: "Prognostic significance of genome-wide DNA methylation profiles within the randomised, phase 3, EORTC CATNON trial on non-1p19q deleted anaplastic glioma",... by Neuro-Oncology: The Podcast
18 min listen
Glioblastoma subtypes and response to Dasatinib: Dr. Evan Noch interviews Drs. Emma Phillips and Violaine Goidts about their recent manuscript entitled "A Novel Patient Stratification Strategy to Enhance the Therapeutic Efficacy of Dasatinib in Glioblastoma", published online in... by Neuro-Oncology: The Podcast
22 min listen

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Immunotherapy drives mesenchymal shift in GBM

Immunotherapy drives mesenchymal shift in GBM

Description

Titles in the series (82)

More Episodes from Neuro-Oncology: The Podcast

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