PTEN deficiency and proteosome addiction in glioblastoma

FromNeuro-Oncology: The Podcast

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PTEN deficiency and proteosome addiction in glioblastoma

FromNeuro-Oncology: The Podcast

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Length:

23 minutes

Released:

Mar 12, 2021

Format:

Podcast episode

Description

Dr. Evan Noch interviews Drs. Frank Furnari and Jorge Benitez about their recent paper: "PTEN deficiency leads to proteosome addiction, a novel vulnerability in glioblastoma" published online in Neuro-Oncology in January, 2021.

Released:

Mar 12, 2021

Format:

Podcast episode

Titles in the series (79)

Neuro-Oncology: The Podcast will keep you up to date about the latest advances in the field as we present conversations with the authors of selected papers from Neuro-Oncology and its sister journals, Neuro-Oncology Practice and Neuro-Oncology Advances.

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33 min listen
DNA methylation profiles within the CATNON trial: Dr. Iyad Alnahhas interviews Dr. Pim French about his and his team recent manuscript entitled: "Prognostic significance of genome-wide DNA methylation profiles within the randomised, phase 3, EORTC CATNON trial on non-1p19q deleted anaplastic glioma",... by Neuro-Oncology: The Podcast
18 min listen
A prospective phase II randomized trial of proton radiotherapy vs intensity modulated radiotherapy for patients with newly diagnosed GBM: Dr. Jasmin Jo interviews Dr. Caroline Chung about her paper: “A prospective phase II randomized trial of proton radiotherapy vs intensity modulated radiotherapy for patients with newly diagnosed GBM” published online in Neuro-Oncology in Feb 2021. by Neuro-Oncology: The Podcast
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Testing methods for MGMT promoter methylation: Dr. Iyad Alnahhas interviews Dr. Kathreena Kurian about her and her team's recent manuscript entitled: "MGMT promoter methylation testing to predict overall survival in people with glioblastoma treated with temozolomide: a comprehensive meta-analysis... by Neuro-Oncology: The Podcast
13 min listen
The incidence of brain metastases among patients with metastatic breast cancer: Dr. Iyad Alnahhas interviews Dr. Katarzyna Jerzak about her recent paper “The incidence of brain metastases among patients with metastatic breast cancer: a systematic review and meta-analysis”, published online in Neuro-Oncology in December,... by Neuro-Oncology: The Podcast
24 min listen
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26 min listen
Cold-Inducible RNA-Binding Protein expression and recurrence of brain metastases: Dr. Alireza Mansouri interviews Dr. Matthew Dankner about his recent paper "Invasive growth associated with Cold-Inducible RNA-Binding Protein expression drives recurrence of surgically resected brain metastases" published online in Neuro-Oncology in... by Neuro-Oncology: The Podcast
11 min listen
Supratotal resection of lower-grade gliomas: Dr. Alireza Mansouri talks with Dr. Lorenzo Bello about his recently published article in Neuro-Oncology entitled: "Association of Supratotal Resection with Progression-Free Survival, Malignant Transformation, and Overall Survival in Lower-Grade... by Neuro-Oncology: The Podcast
19 min listen
A subset of pediatric thalamic gliomas: Dr. Iyad Alnahhas talks with Dr. Felix Sahm about his recently published article in Neuro-Oncology entitled: "A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR,"... by Neuro-Oncology: The Podcast
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Brain radiotherapy and decline in fine motor skills: Dr. Iyad Alnahhas interviews Dr. Jona Hattangadi-Gluth and Ms. Mia Salans about their recently published manuscript entitled: "Longitudinal change in fine motor skills after brain radiotherapy and in vivo imaging biomarkers associated with... by Neuro-Oncology: The Podcast
18 min listen
Temozolomide-induced hypermutation in IDH-mutant low-grade gliomas: Dr. Maya Graham interviews Dr. Nancy Ann Oberheim Bush about her and her team's paper entitled " Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant... by Neuro-Oncology: The Podcast
13 min listen
A serum based DNA methylation assay to detect gliomas: Dr. Iyad Alnahhas interviews Dr. Houton Noushmehr about his recent paper "A serum-based DNA methylation assay provides accurate detection of glioma", published online in Feb 2021 in Neuro-Oncology by Neuro-Oncology: The Podcast
33 min listen
Loss of H3K27me3 in the Tübingen meningioma cohort: Dr. Maya Graham interviews Drs. Ghazaleh Tabatabai and Felix Behling about their paper entitled “H3K27me3 loss indicates an increased risk of recurrence in the Tübingen meningioma cohort” published online in Neuro-Oncology in December 2020. by Neuro-Oncology: The Podcast
18 min listen
PTEN deficiency and proteosome addiction in glioblastoma: Dr. Evan Noch interviews Drs. Frank Furnari and Jorge Benitez about their recent paper: "PTEN deficiency leads to proteosome addiction, a novel vulnerability in glioblastoma" published online in Neuro-Oncology in January, 2021. by Neuro-Oncology: The Podcast
23 min listen
A large longitudinal study of patients with Neurofibromatosis Type 2.: Dr. Iyad Alnahhas interviews Dr. Gareth Evans about his recent paper in Neuro-Oncology entitled: "Disease course of Neurofibromatosis Type 2; a 30-year follow-up study of 353 patients seen at a single institution by Neuro-Oncology: The Podcast
21 min listen
Molecular signatures of glioma causation: Dr. Evan Noch interviews Dr. Elizabeth Claus about her recent manuscript entitled: "Environmental and sex-specific molecular signatures of glioma causation" published online in Neuro-Oncology in May 2021. by Neuro-Oncology: The Podcast
22 min listen
Checkpoint blockade in atypical meningiomas: Description: Dr. Nicholas Butowski interviews Dr. David Reardon about his recent manuscript "Activity of PD-1 blockade with nivolumab among patients with recurrent atypical/anaplastic meningioma: phase II trial results", published online in... by Neuro-Oncology: The Podcast
40 min listen
18F FET PET in childhood CNS tumors: Description: Dr. Maya Graham interviews Dr. Lisbeth Marner about her recent manuscript "" Diagnostic accuracy and clinical impact of 18F FET PET in childhood CNS tumors" " published online in April 2021 in Neuro-Oncology. by Neuro-Oncology: The Podcast
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33 min listen
Epidemiology of Brainstem High-Grade Gliomas in Children and Adolescents in the United States, 2000-2017: Dr. Evan Noch interviews Dr. Jill Barnholtz-Sloan about her recent paper "Epidemiology of Brainstem High-Grade Gliomas in Children and Adolescents in the United States, 2000-2017" published online in Neuro-Oncology in December 2020. by Neuro-Oncology: The Podcast
17 min listen
Loss of H3K27me3 in meningiomas: Dr. Evan Noch interviews Drs. Farshad Nassiri and Justin Wang from the team of Dr. Gelareh Zadeh about their recently published paper entitled “Loss of H3K27me3 in meningiomas” published online in Neuro-Oncology in May 2021. by Neuro-Oncology: The Podcast
26 min listen
BOLD fMRI in IDH mutant gliomas: Dr. Ankush Bhatia interviews Dr. Jack Grinband about his recent manuscript entitled "BOLD Asynchrony Elucidates Tumor Burden in IDH-Mutated Gliomas", published online in Neuro-Oncology in July 2021 by Neuro-Oncology: The Podcast
29 min listen
Immunosuppression in IDH mutant gliomas: Dr. Maya Graham interviews Dr. Nduka Amankulor about the recent manuscript entitled: "Characterization of systemic immunosuppression by IDH mutant glioma small extracellular vesicles" published online in Neuro-Oncology in July 2021. by Neuro-Oncology: The Podcast
30 min listen
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Cell-free DNA from CSF in pediatric, adolescent and young adult patients: Dr. Iyad Alnahhas interviews Dr. Matthias Karajannis about his and his team's recent manuscript entitled: "Next-generation sequencing of cerebrospinal fluid for clinical molecular diagnostics in pediatric, adolescent and young adult (AYA) brain tumor... by Neuro-Oncology: The Podcast
11 min listen
Moleculary integrated grading for meningioma: Dr. Nicholas Butowski interviews Drs. Sandro Santagata and Wenya Linda Bi about their recent manuscript entitled: "A molecularly integrated grade for meningioma", published online in Neuro-Oncology in September 2021. by Neuro-Oncology: The Podcast
29 min listen
Selumetinib in children with NF1 and plexiform neurofibroma: Dr.Iyad Alnahhas interviews Drs. Andrea Gross and Brigitte Widemann about their manuscript entitled "Selumetinib in Children with Neurofibromatosis Type 1 and Asymptomatic Inoperable Plexiform Neurofibroma at Risk for Developing Tumor-Related... by Neuro-Oncology: The Podcast
24 min listen
The clinical utility of next generation sequencing for IDHwt glioblastoma: Dr. Evan Noch interviews Dr. Mary Jane Lim-Fat about her and her team's recent manuscript entitled: "Clinical utility of targeted next generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making", published online in... by Neuro-Oncology: The Podcast
22 min listen

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PTEN deficiency and proteosome addiction in glioblastoma

PTEN deficiency and proteosome addiction in glioblastoma

Description

Titles in the series (79)

More Episodes from Neuro-Oncology: The Podcast