Moderator: Massimo Filippi (Milan, Italy)Guest: Federica Agosta (Milan, Italy)In this week’s episode Prof. Massimo Filippi and Prof. Federica Agosta discuss frontotemporal dementia (FTD) emphasizing the role of neuroimaging (MRI and FDG PET) in early diagnosis. They highlight MRI for identifying crucial patterns and FDG PET for detecting metabolic changes. Early detection is crucial for future treatments. Connectomics, studying brain networks, aids in predicting FTD progression. Emerging PET tracers, like UCBJ, show promise for early neurodegeneration markers. The episode is a valuable resource for neurologists interested in FTD diagnostics and monitoring.