Moderator: Alberto Vogrig (Udine, Italy)Guest: Giulia Berzero (Milan, Italy)In this episode Dr. Alberto Vogrig is joined by Dr. Giulia Berzero to discuss the clinical approach to neurological symptoms in patients with cancer. She highlights the increasing occurrence of neurological complications in cancer patients due to improved survival rates and novel cancer treatments. Dr. Berzero emphasizes the importance of considering patient-related factors, tumor-related factors, and treatment modalities in assessing the risk of developing neurological symptoms. She also explains the signs that may prompt suspicion of brain metastasis and provides guidance on assessing and diagnosing CNS dissemination in cancer patients. Dr. Berzero stresses the need for a multidisciplinary approach and collaboration with oncologists to optimize patient care.