In this episode of SurgOnc Today®, Julie Hallet, MD, MSc, FRCSC, FSSO, from the University of Toronto and Vice-Chair of the SSO HPB disease site working group is joined by Stefano Partelli, MD, PhD, from Università Vita-Saluta San Raffaele and Els Nieveen van Dijkum, MD, PhD, from Amsterdam UMC. We will delve into the rationale behind the non-operative management of non-functional sporadic pancreatic neuroendocrine tumors (PNETs) as well as the design and results of two prospective studies, ASPEN and PANDORA. Show Notes: PANDORA: https://academic.oup.com/bjs/article/108/8/888/6202974 ASPEN (interim analysis): https://academic.oup.com/bjs/article/109/12/1186/6672718?login=false