Ever wondered why embryos fail to implant? Would a euploid embryo overcome this problem? In this December 2020 Fertility and Sterility article by Pirtea et al., which was also featured in a recent Journal Club Global, the authors discuss their study of the true prevalence of recurrent implantation failure. This Fertility and Sterility On Air episode discusses the findings and clinical impact with the authors. View the Journal Club Webinar at https://www.asrm.org/resources/videos/educational-webinars/journal-club-global/recurrent-implantation-failures-in-art-myth-or-reality/ Visit Fertility and Sterility at https://www.fertstert.org/