A scientist and a comedian walk into a bar—for an interview about the craft of science comedy. Ira talks to comedians Chuck Nice, Kasha Patel, and Kyle Marian Viterbo about their work bringing the joke format to science communication. While all three have different approaches to science—whether it’s sneaking the knowledge into “regular” jokes, or going straight for the factual jugular—they agree that the practice of stand-up has much in common with the scientific process. “We normally start with an observation or a question,” says Nice. “The experimentation is the joke itself, seeing whether or not it will get a laugh… you have to tell it in front of an audience. And after that you go, ‘Wow, that sucked. I can’t believe that wasn’t funny.’”Plus, why comedy can itself be a science, and what good comedy has in common with good (science) communication.“It’s a long term skillset in playing with, and communicating, and connecting with your audience,” says Viterbo. “To be able to really listen to our audience, which these days we need more of.”Universe of Art is hosted and produced by D. Peterschmidt, who also wrote the music. The original segment was produced by Christie Taylor. Our show art was illustrated by Abelle Hayford. Support for Science Friday’s science and arts coverage comes from the Alfred P. Sloan Foundation. Do you have science-inspired art you’d like to share with us for a future episode? Send us an email or a voice memo to universe@sciencefriday.com.