Mark DeWitt and Don Kohn Discuss Their ex vivo CRISPR-based Therapy to Cure Sickle Cell Anemia

Alex Philippidis Reviews Trends in Biopharma & Biotech Market: Biotech and biopharma companies are in a phase of accelerated growth. Alex Philippidis, a science journalist at Genetic Engineering & Biotechnology News discusses the changing face of big pharma, biotech, and CRISPR gene editing industries, as they raise... by CRISPR Cuts

28 min listen

Reed Kelso Strives to Enable CRISPR Access For All Scientists: Reed Kelso, Head of Cell Engineering Research and Applications at Synthego, is a bio-wizard. In this episode, Kevin & Minu catch up with Reed about his role at Synthego and the day-to-day operations at the fast paced start-up. Reed talks about the revolu... by CRISPR Cuts

16 min listen

CRISPR for Curious Minds by CRISPR Cuts

41 min listen

CRISPR in Gene Drives: Experts Opine: Gene drives have frequently been in the news in the past few years. In this episode, we discuss what exactly gene drives are, their applications, and how scientists are ensuring that they are used responsibly. Tune in to hear what researchers Anna Buchma... by CRISPR Cuts

11 min listen

Avery Posey Discusses CAR T Cell Cancer Therapies: Dr. Avery Posey is leading the charge on CAR T cell therapy research to bring this technology to cancer patients as soon as possible. Learn how CAR T works, what stage it’s in now, and how it will help revolutionize the treatment of cancer. by CRISPR Cuts

25 min listen

Knockout Cell Pools Are Simplifying CRISPR Experiments: Dr. Ania Wronski, Product Manager for the Engineered Cells portfolio at Synthego, discusses how their new engineered cells products are enabling CRISPR access to researchers worldwide. Learn about the different ways in which researchers use knockout cell... by CRISPR Cuts

21 min listen

Michael Friend Advocates For Diversity in CRISPR: In this episode, Michael Friend, CEO of Minority Coalition for Precision Medicine, discusses the lack of diversity in genome editing field and covers potential solutions for ensuring an inclusive future, particularly for black scientists. by CRISPR Cuts

19 min listen

Leading St. Jude's Genome Engineering Capabilities: A Chat with Shondra Miller: Shondra Miller shares her experience of starting a shared genome engineering resource at the St. Jude Children's Research Hospital. Learn more about her research projects and her views on the past, present, and future of the genome editing field in this ... by CRISPR Cuts

10 min listen

CRISPR in Fungi: An Interview with Rebecca Shapiro: Rebecca Shapiro, Assistant Professor at the University of Guelph, talks about CRISPR genome editing in fungal pathogens to understand their disease-causing mechanism. Her lab also works on gene drives in fungi for studying large scale genetic interaction... by CRISPR Cuts

18 min listen

The Potential of CRISPR Editing in Stem Cells: An Interview with Bill Skarnes: Dr. Bill Skarnes, Professor at The Jackson Laboratory, chats about how CRISPR edited stem cells are becoming a gold standard to study gene function and disease modeling. by CRISPR Cuts

13 min listen

Improving Targeted Delivery to Enhance Personalized Medicine: Andre Watson, CEO of Ligandal, talks about how his company is improving the payload delivery of gene therapy, making it more accurate and efficient, to make new gene therapy a reality for the public. by CRISPR Cuts

28 min listen

Christian Groendahl On Pioneering a CRISPR-based Microbial Gene Therapy: Tune in to hear Christian Groendahl, CEO of SNIPR Biome, talk about CRISPR editing in prokaryotes, their novel E. coli-targeting CRISPR therapy trials, and his experiences and vision leading a start up. by CRISPR Cuts

29 min listen

CRISPR Forecast 2021 with Paul Dabrowski and Robert Deans: In this episode, Paul Dabrowski, CEO of Synthego, and Robert Deans, CSO of Synthego, discuss the CRISPR silver linings of 2020 and predict the directions and milestones for gene editing in 2021. by CRISPR Cuts

18 min listen

Making of a CRISPR Film: Behind the Scenes with Producers of Human Nature: What is the process to make a science film? In this episode, Sarah Goodwin and Elliot Kirschner, producers of Human Nature, a documentary on CRISPR, offer glimpses into making of the film. by CRISPR Cuts

38 min listen

Neville Sanjana Discusses Ways to Enhance CRISPR-Cas13 Knockdown in Human Cells: In this collaboration episode with NEB, we interview Dr. Neville Sanjana, a core faculty member at the New York Genome Center, about his recent publication in which chemically modified guide RNAs were used to enhance CRISPR-Cas13 knockdown in human cells... by CRISPR Cuts

33 min listen

CRISPR Office Hours with Hamid Ghanadaan: The COVID-19 pandemic is a unique situation for lab scientists, many of whose work has come to a standstill. Hamid Ghanadaan, CEO of Linus, discusses the impact of COVID-19 on science and the next steps for scientists, based on their survey of >1000 scie... by CRISPR Cuts

36 min listen

Kevin Davies Chats About His Latest Book "Editing Humanity": Kevin Davies, the executive editor of The CRISPR Journal, has closely watched the genetics space evolve over the last decades. His expertise and experience were the perfect foundation for his latest book "Editing Humanity: The CRISPR Revolution and the N... by CRISPR Cuts

32 min listen

6 Women CRISPR Leaders Get Candid About Their Journeys to the Top: We chatted with six female leaders in the CRISPR—Alison van Eenennaam, Ph.D., Kiana Aran, Christina Trojel-Hansen, Ph.D., Laura Lambert, Ph.D., Elena Miñones Moyano, Ph.D., and Samantha Maragh, Ph.D.— about their professional journeys. Tune in to this e... by CRISPR Cuts

63 min listen

Jesse Boehm Discusses Tackling Rare Cancers Using CRISPR: In this CRISPR Cuts episode, Dr. Jesse Boehm, the Chief Scientific Officer of the Break Through Cancer Foundation and principal investigator at the Broad Institute, talks about his work on rare cancers. He also covers how CRISPR technology is transformin... by CRISPR Cuts

31 min listen

NIH Scientists Discuss the iNDI Project for Alzheimer's Disease Modeling: The Inducible Pluripotent Stem Cell Neurodegeneration Initiative (iNDI), an NIH effort, aims to standardize disease models for Alzheimer’s and related dementias. Hear the principal contributors, Dr. Michael E. Ward and Dr. Mark R. Cookson, scientists at ... by CRISPR Cuts

37 min listen

TJ Cradick Speaks About Their HIV CRISPR Therapy in Trials: TJ Cradick, Chief Scientific Officer at Excision Bio, discusses their CRISPR HIV therapy that recently proceeded into clinical trials in this episode and their ongoing work on other viral diseases. by CRISPR Cuts

24 min listen

Jimi Olaghere Opens up About His Sickle Cell Disease and CRISPR Trial: Jimi has dealt with sickle cell disease, a genetic disorder with serious implications, his entire life. Undergoing a CRISPR gene editing trial turned his hope for a cure into reality with promising results from the early phases. Tune in to learn about Ji... by CRISPR Cuts

40 min listen

Ayal Hendel Talks About CRISPR in Bubble Boy Disease: Dr. Ayal Hendel, a genome-editing pioneer and group leader at Bar Ilan University in Israel, was one of the first researchers to use modified synthetic sgRNA to edit primary cells with CRISPR. In this episode, Dr. Hendel shares his perspectives on the re... by CRISPR Cuts

36 min listen

Joe Miano Talks About Prime Editing in Mice: Prime editing is a new genome engineering tool that emerged just a couple of years back. Right from the get-go, this technology made waves as a potential alternative to CRISPR. Now, the first comparative study in mice is out. Dr. Joe Miano, Professor at ... by CRISPR Cuts

20 min listen

Kiana Aran Chats About her Nature Award and New Non-Profit: In this episode, we chat with Dr. Kiana Aran, the CSO of Cardea Bio and associate professor at Keck Graduate Institute, who recently won the Nature Research Award for Inspiring Women in Science. Dr. Aran talks about her experience being a nominee and awa... by CRISPR Cuts

41 min listen

Bryce Olson Relays His Experience on Personalized Therapies for Cancer Patients: After being diagnosed with aggressive prostate cancer, Bryce Olson quickly learned the science behind it and has leveraged NGS to understand his tumor genomics and find opportunities in personalized therapies. Hear the patient perspective for the first t... by CRISPR Cuts

43 min listen

Stephanie Cherqui Discusses Clinical Development of CRISPR Therapies for Rare Diseases by CRISPR Cuts

20 min listen

Mark DeWitt and Don Kohn Discuss Their ex vivo CRISPR-based Therapy to Cure Sickle Cell Anemia: Dr. Mark DeWitt Ph.D., Associate Director at Mammoth Biosciences, and Dr. Don Kohn M.D., distinguished professor and Director of the UCLA Human Gene and Cell Therapy Program and CIRM grantee sat down with us to discuss their latest clinical trials to... by CRISPR Cuts

33 min listen

Bryan Dechairo Envisions an Accessible Future for CRISPR Diagnostics: In this episode, Bryan Dechairo, CEO of Sherlock Biosciences, talks about the impact of technology advances in the field of CRISPR diagnostics, his experiences leading Sherlock Biosciences, and his team’s mission of accessibility. by CRISPR Cuts

35 min listen

Sunil Sharma and Raffaella Soldi Talk CRISPR For Unbiased Drug Screening for Rare Pediatric Cancers: Dr. Sunil Sharma and Dr. Raffaella Soldi of the Translational Genomics Research Institute chat about using CRISPR arrayed screens to identify novel drug targets for Ewing's Sarcoma, outlooks for the future of cancer therapies, and the Arizona heat. by CRISPR Cuts

25 min listen

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Mark DeWitt and Don Kohn Discuss Their ex vivo CRISPR-based Therapy to Cure Sickle Cell Anemia

Mark DeWitt and Don Kohn Discuss Their ex vivo CRISPR-based Therapy to Cure Sickle Cell Anemia

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