Christian Groendahl On Pioneering a CRISPR-based Microbial Gene Therapy

FromCRISPR Cuts

Start listening View podcast show

Christian Groendahl On Pioneering a CRISPR-based Microbial Gene Therapy

FromCRISPR Cuts

ratings:

Length:

29 minutes

Released:

Dec 5, 2022

Format:

Podcast episode

Description

Tune in to hear Christian Groendahl, CEO of SNIPR Biome, talk about CRISPR editing in prokaryotes, their novel E. coli-targeting CRISPR therapy trials, and his experiences and vision leading a start up.

Released:

Dec 5, 2022

Format:

Podcast episode

Titles in the series (32)

Welcome to the CRISPR revolution. Take a break and join us as we guide conversations with an expert CRISPR cast about this cutting-edge science.

Skip carousel

CRISPR for Curious Minds by CRISPR Cuts
41 min listen
Alex Philippidis Reviews Trends in Biopharma & Biotech Market: Biotech and biopharma companies are in a phase of accelerated growth. Alex Philippidis, a science journalist at Genetic Engineering & Biotechnology News discusses the changing face of big pharma, biotech, and CRISPR gene editing industries, as they raise... by CRISPR Cuts
28 min listen
Knockout Cell Pools Are Simplifying CRISPR Experiments: Dr. Ania Wronski, Product Manager for the Engineered Cells portfolio at Synthego, discusses how their new engineered cells products are enabling CRISPR access to researchers worldwide. Learn about the different ways in which researchers use knockout cell... by CRISPR Cuts
21 min listen
Reed Kelso Strives to Enable CRISPR Access For All Scientists: Reed Kelso, Head of Cell Engineering Research and Applications at Synthego, is a bio-wizard. In this episode, Kevin & Minu catch up with Reed about his role at Synthego and the day-to-day operations at the fast paced start-up. Reed talks about the revolu... by CRISPR Cuts
16 min listen
CRISPR in Gene Drives: Experts Opine: Gene drives have frequently been in the news in the past few years. In this episode, we discuss what exactly gene drives are, their applications, and how scientists are ensuring that they are used responsibly. Tune in to hear what researchers Anna Buchma... by CRISPR Cuts
11 min listen
Avery Posey Discusses CAR T Cell Cancer Therapies: Dr. Avery Posey is leading the charge on CAR T cell therapy research to bring this technology to cancer patients as soon as possible. Learn how CAR T works, what stage it’s in now, and how it will help revolutionize the treatment of cancer. by CRISPR Cuts
25 min listen
CRISPR in Fungi: An Interview with Rebecca Shapiro: Rebecca Shapiro, Assistant Professor at the University of Guelph, talks about CRISPR genome editing in fungal pathogens to understand their disease-causing mechanism. Her lab also works on gene drives in fungi for studying large scale genetic interaction... by CRISPR Cuts
18 min listen
CRISPR Forecast 2021 with Paul Dabrowski and Robert Deans: In this episode, Paul Dabrowski, CEO of Synthego, and Robert Deans, CSO of Synthego, discuss the CRISPR silver linings of 2020 and predict the directions and milestones for gene editing in 2021. by CRISPR Cuts
18 min listen
The Potential of CRISPR Editing in Stem Cells: An Interview with Bill Skarnes: Dr. Bill Skarnes, Professor at The Jackson Laboratory, chats about how CRISPR edited stem cells are becoming a gold standard to study gene function and disease modeling. by CRISPR Cuts
13 min listen
Improving Targeted Delivery to Enhance Personalized Medicine: Andre Watson, CEO of Ligandal, talks about how his company is improving the payload delivery of gene therapy, making it more accurate and efficient, to make new gene therapy a reality for the public. by CRISPR Cuts
28 min listen
Leading St. Jude's Genome Engineering Capabilities: A Chat with Shondra Miller: Shondra Miller shares her experience of starting a shared genome engineering resource at the St. Jude Children's Research Hospital. Learn more about her research projects and her views on the past, present, and future of the genome editing field in this ... by CRISPR Cuts
10 min listen
CRISPR Office Hours with Hamid Ghanadaan: The COVID-19 pandemic is a unique situation for lab scientists, many of whose work has come to a standstill. Hamid Ghanadaan, CEO of Linus, discusses the impact of COVID-19 on science and the next steps for scientists, based on their survey of >1000 scie... by CRISPR Cuts
36 min listen
Making of a CRISPR Film: Behind the Scenes with Producers of Human Nature: What is the process to make a science film? In this episode, Sarah Goodwin and Elliot Kirschner, producers of Human Nature, a documentary on CRISPR, offer glimpses into making of the film. by CRISPR Cuts
38 min listen
Kiana Aran Chats About her Nature Award and New Non-Profit: In this episode, we chat with Dr. Kiana Aran, the CSO of Cardea Bio and associate professor at Keck Graduate Institute, who recently won the Nature Research Award for Inspiring Women in Science. Dr. Aran talks about her experience being a nominee and awa... by CRISPR Cuts
41 min listen
Bryce Olson Relays His Experience on Personalized Therapies for Cancer Patients: After being diagnosed with aggressive prostate cancer, Bryce Olson quickly learned the science behind it and has leveraged NGS to understand his tumor genomics and find opportunities in personalized therapies. Hear the patient perspective for the first t... by CRISPR Cuts
43 min listen
Michael Friend Advocates For Diversity in CRISPR: In this episode, Michael Friend, CEO of Minority Coalition for Precision Medicine, discusses the lack of diversity in genome editing field and covers potential solutions for ensuring an inclusive future, particularly for black scientists. by CRISPR Cuts
19 min listen
Jesse Boehm Discusses Tackling Rare Cancers Using CRISPR: In this CRISPR Cuts episode, Dr. Jesse Boehm, the Chief Scientific Officer of the Break Through Cancer Foundation and principal investigator at the Broad Institute, talks about his work on rare cancers. He also covers how CRISPR technology is transformin... by CRISPR Cuts
31 min listen
Jimi Olaghere Opens up About His Sickle Cell Disease and CRISPR Trial: Jimi has dealt with sickle cell disease, a genetic disorder with serious implications, his entire life. Undergoing a CRISPR gene editing trial turned his hope for a cure into reality with promising results from the early phases. Tune in to learn about Ji... by CRISPR Cuts
40 min listen
Joe Miano Talks About Prime Editing in Mice: Prime editing is a new genome engineering tool that emerged just a couple of years back. Right from the get-go, this technology made waves as a potential alternative to CRISPR. Now, the first comparative study in mice is out. Dr. Joe Miano, Professor at ... by CRISPR Cuts
20 min listen
Kevin Davies Chats About His Latest Book "Editing Humanity": Kevin Davies, the executive editor of The CRISPR Journal, has closely watched the genetics space evolve over the last decades. His expertise and experience were the perfect foundation for his latest book "Editing Humanity: The CRISPR Revolution and the N... by CRISPR Cuts
32 min listen
NIH Scientists Discuss the iNDI Project for Alzheimer's Disease Modeling: The Inducible Pluripotent Stem Cell Neurodegeneration Initiative (iNDI), an NIH effort, aims to standardize disease models for Alzheimer’s and related dementias. Hear the principal contributors, Dr. Michael E. Ward and Dr. Mark R. Cookson, scientists at ... by CRISPR Cuts
37 min listen
TJ Cradick Speaks About Their HIV CRISPR Therapy in Trials: TJ Cradick, Chief Scientific Officer at Excision Bio, discusses their CRISPR HIV therapy that recently proceeded into clinical trials in this episode and their ongoing work on other viral diseases. by CRISPR Cuts
24 min listen
Ayal Hendel Talks About CRISPR in Bubble Boy Disease: Dr. Ayal Hendel, a genome-editing pioneer and group leader at Bar Ilan University in Israel, was one of the first researchers to use modified synthetic sgRNA to edit primary cells with CRISPR. In this episode, Dr. Hendel shares his perspectives on the re... by CRISPR Cuts
36 min listen
Bryan Dechairo Envisions an Accessible Future for CRISPR Diagnostics: In this episode, Bryan Dechairo, CEO of Sherlock Biosciences, talks about the impact of technology advances in the field of CRISPR diagnostics, his experiences leading Sherlock Biosciences, and his team’s mission of accessibility. by CRISPR Cuts
35 min listen
Neville Sanjana Discusses Ways to Enhance CRISPR-Cas13 Knockdown in Human Cells: In this collaboration episode with NEB, we interview Dr. Neville Sanjana, a core faculty member at the New York Genome Center, about his recent publication in which chemically modified guide RNAs were used to enhance CRISPR-Cas13 knockdown in human cells... by CRISPR Cuts
33 min listen
6 Women CRISPR Leaders Get Candid About Their Journeys to the Top: We chatted with six female leaders in the CRISPR—Alison van Eenennaam, Ph.D., Kiana Aran, Christina Trojel-Hansen, Ph.D., Laura Lambert, Ph.D., Elena Miñones Moyano, Ph.D., and Samantha Maragh, Ph.D.— about their professional journeys. Tune in to this e... by CRISPR Cuts
63 min listen
Imran House and Junyun Lai Discuss CRISPR Screening in Immuno-Oncology: Imran House, Ph.D. and Junyun Lai Ph.D. are Senior Scientists at the biotech start-up, ONKo-Innate in Melbourne, Australia that focuses on developing immuno-oncology therapies. In this episode they discussed what they do at oNKo-innate, their career ... by CRISPR Cuts
26 min listen
Stephanie Cherqui Discusses Clinical Development of CRISPR Therapies for Rare Diseases by CRISPR Cuts
20 min listen
Dina Simkin Breaks Down Epilepsy Cell Modeling: Dina Simkin, Professor of Neurology at Northwestern University, joins us in this episode of CRISPR Cuts. Dr. Simkin talks about her path to becoming a researcher, art, and the importance of patient and isogenic iPSC models to study genetically linked... by CRISPR Cuts
27 min listen
Christian Groendahl On Pioneering a CRISPR-based Microbial Gene Therapy: Tune in to hear Christian Groendahl, CEO of SNIPR Biome, talk about CRISPR editing in prokaryotes, their novel E. coli-targeting CRISPR therapy trials, and his experiences and vision leading a start up. by CRISPR Cuts
29 min listen

More Episodes from CRISPR Cuts

Skip carousel

Imran House and Junyun Lai Discuss CRISPR Screening in Immuno-Oncology: Imran House, Ph.D. and Junyun Lai Ph.D. are Senior Scientists at the biotech start-up, ONKo-Innate in Melbourne, Australia that focuses on developing immuno-oncology therapies. In this episode they discussed what they do at oNKo-innate, their career ... by CRISPR Cuts
26 min listen
Mark DeWitt and Don Kohn Discuss Their ex vivo CRISPR-based Therapy to Cure Sickle Cell Anemia: Dr. Mark DeWitt Ph.D., Associate Director at Mammoth Biosciences, and Dr. Don Kohn M.D., distinguished professor and Director of the UCLA Human Gene and Cell Therapy Program and CIRM grantee sat down with us to discuss their latest clinical trials to... by CRISPR Cuts
33 min listen
Dina Simkin Breaks Down Epilepsy Cell Modeling: Dina Simkin, Professor of Neurology at Northwestern University, joins us in this episode of CRISPR Cuts. Dr. Simkin talks about her path to becoming a researcher, art, and the importance of patient and isogenic iPSC models to study genetically linked... by CRISPR Cuts
27 min listen
Sunil Sharma and Raffaella Soldi Talk CRISPR For Unbiased Drug Screening for Rare Pediatric Cancers: Dr. Sunil Sharma and Dr. Raffaella Soldi of the Translational Genomics Research Institute chat about using CRISPR arrayed screens to identify novel drug targets for Ewing's Sarcoma, outlooks for the future of cancer therapies, and the Arizona heat. by CRISPR Cuts
25 min listen
Stephanie Cherqui Discusses Clinical Development of CRISPR Therapies for Rare Diseases by CRISPR Cuts
20 min listen
Bryan Dechairo Envisions an Accessible Future for CRISPR Diagnostics: In this episode, Bryan Dechairo, CEO of Sherlock Biosciences, talks about the impact of technology advances in the field of CRISPR diagnostics, his experiences leading Sherlock Biosciences, and his team’s mission of accessibility. by CRISPR Cuts
35 min listen
Ayal Hendel Talks About CRISPR in Bubble Boy Disease: Dr. Ayal Hendel, a genome-editing pioneer and group leader at Bar Ilan University in Israel, was one of the first researchers to use modified synthetic sgRNA to edit primary cells with CRISPR. In this episode, Dr. Hendel shares his perspectives on the re... by CRISPR Cuts
36 min listen
Jimi Olaghere Opens up About His Sickle Cell Disease and CRISPR Trial: Jimi has dealt with sickle cell disease, a genetic disorder with serious implications, his entire life. Undergoing a CRISPR gene editing trial turned his hope for a cure into reality with promising results from the early phases. Tune in to learn about Ji... by CRISPR Cuts
40 min listen
TJ Cradick Speaks About Their HIV CRISPR Therapy in Trials: TJ Cradick, Chief Scientific Officer at Excision Bio, discusses their CRISPR HIV therapy that recently proceeded into clinical trials in this episode and their ongoing work on other viral diseases. by CRISPR Cuts
24 min listen
Bryce Olson Relays His Experience on Personalized Therapies for Cancer Patients: After being diagnosed with aggressive prostate cancer, Bryce Olson quickly learned the science behind it and has leveraged NGS to understand his tumor genomics and find opportunities in personalized therapies. Hear the patient perspective for the first t... by CRISPR Cuts
43 min listen
Neville Sanjana Discusses Ways to Enhance CRISPR-Cas13 Knockdown in Human Cells: In this collaboration episode with NEB, we interview Dr. Neville Sanjana, a core faculty member at the New York Genome Center, about his recent publication in which chemically modified guide RNAs were used to enhance CRISPR-Cas13 knockdown in human cells... by CRISPR Cuts
33 min listen
Kiana Aran Chats About her Nature Award and New Non-Profit: In this episode, we chat with Dr. Kiana Aran, the CSO of Cardea Bio and associate professor at Keck Graduate Institute, who recently won the Nature Research Award for Inspiring Women in Science. Dr. Aran talks about her experience being a nominee and awa... by CRISPR Cuts
41 min listen
6 Women CRISPR Leaders Get Candid About Their Journeys to the Top: We chatted with six female leaders in the CRISPR—Alison van Eenennaam, Ph.D., Kiana Aran, Christina Trojel-Hansen, Ph.D., Laura Lambert, Ph.D., Elena Miñones Moyano, Ph.D., and Samantha Maragh, Ph.D.— about their professional journeys. Tune in to this e... by CRISPR Cuts
63 min listen
Jesse Boehm Discusses Tackling Rare Cancers Using CRISPR: In this CRISPR Cuts episode, Dr. Jesse Boehm, the Chief Scientific Officer of the Break Through Cancer Foundation and principal investigator at the Broad Institute, talks about his work on rare cancers. He also covers how CRISPR technology is transformin... by CRISPR Cuts
31 min listen
NIH Scientists Discuss the iNDI Project for Alzheimer's Disease Modeling: The Inducible Pluripotent Stem Cell Neurodegeneration Initiative (iNDI), an NIH effort, aims to standardize disease models for Alzheimer’s and related dementias. Hear the principal contributors, Dr. Michael E. Ward and Dr. Mark R. Cookson, scientists at ... by CRISPR Cuts
37 min listen
Joe Miano Talks About Prime Editing in Mice: Prime editing is a new genome engineering tool that emerged just a couple of years back. Right from the get-go, this technology made waves as a potential alternative to CRISPR. Now, the first comparative study in mice is out. Dr. Joe Miano, Professor at ... by CRISPR Cuts
20 min listen
Kevin Davies Chats About His Latest Book "Editing Humanity": Kevin Davies, the executive editor of The CRISPR Journal, has closely watched the genetics space evolve over the last decades. His expertise and experience were the perfect foundation for his latest book "Editing Humanity: The CRISPR Revolution and the N... by CRISPR Cuts
32 min listen
Michael Friend Advocates For Diversity in CRISPR: In this episode, Michael Friend, CEO of Minority Coalition for Precision Medicine, discusses the lack of diversity in genome editing field and covers potential solutions for ensuring an inclusive future, particularly for black scientists. by CRISPR Cuts
19 min listen
CRISPR Forecast 2021 with Paul Dabrowski and Robert Deans: In this episode, Paul Dabrowski, CEO of Synthego, and Robert Deans, CSO of Synthego, discuss the CRISPR silver linings of 2020 and predict the directions and milestones for gene editing in 2021. by CRISPR Cuts
18 min listen
CRISPR Office Hours with Hamid Ghanadaan: The COVID-19 pandemic is a unique situation for lab scientists, many of whose work has come to a standstill. Hamid Ghanadaan, CEO of Linus, discusses the impact of COVID-19 on science and the next steps for scientists, based on their survey of >1000 scie... by CRISPR Cuts
36 min listen
Making of a CRISPR Film: Behind the Scenes with Producers of Human Nature: What is the process to make a science film? In this episode, Sarah Goodwin and Elliot Kirschner, producers of Human Nature, a documentary on CRISPR, offer glimpses into making of the film. by CRISPR Cuts
38 min listen
Leading St. Jude's Genome Engineering Capabilities: A Chat with Shondra Miller: Shondra Miller shares her experience of starting a shared genome engineering resource at the St. Jude Children's Research Hospital. Learn more about her research projects and her views on the past, present, and future of the genome editing field in this ... by CRISPR Cuts
10 min listen
The Potential of CRISPR Editing in Stem Cells: An Interview with Bill Skarnes: Dr. Bill Skarnes, Professor at The Jackson Laboratory, chats about how CRISPR edited stem cells are becoming a gold standard to study gene function and disease modeling. by CRISPR Cuts
13 min listen
CRISPR in Fungi: An Interview with Rebecca Shapiro: Rebecca Shapiro, Assistant Professor at the University of Guelph, talks about CRISPR genome editing in fungal pathogens to understand their disease-causing mechanism. Her lab also works on gene drives in fungi for studying large scale genetic interaction... by CRISPR Cuts
18 min listen

Related podcast episodes

Skip carousel

#2 Treating Epilepsy with Whole Plant Cannabis with Dr. Barbara Brett-Green: Can cannabis treat epilepsy? How does it work differently from traditional pharmaceutical drugs? In this episode, we talk to psychologist Dr. Barbara Brett-Green, who recently conducted a study testing the effects of medicinal cannabis on adults with med... by Psychedelic Science for the People
50 min listen
CRISPR by Design with Ben Oakes: Scribe Therapeutics cofounder and CEO Ben Oakes joins a16z Bio + Health founding general partner Vijay Pande. by Raising Health
29 min listen
21. Dr. Jared Speigler, discusses the Myths, Indications, & Science of Hemp CBD.: Dr. Speigler from the Living Proof Institute discusses the myths, indications and medical science of hemp CBD. We discuss how to use it medicinally, and attempt to separate the marketing mania of CBD from the scientific facts and actual clinical uses. by The Dr. Madeira Show
73 min listen
Ayal Hendel Talks About CRISPR in Bubble Boy Disease: Dr. Ayal Hendel, a genome-editing pioneer and group leader at Bar Ilan University in Israel, was one of the first researchers to use modified synthetic sgRNA to edit primary cells with CRISPR. In this episode, Dr. Hendel shares his perspectives on the re... by CRISPR Cuts
36 min listen
#63: Dr. Jill interviews Kiran Krishnan of Megaspore: In Episode #63, Dr. Jill Interviews Kiran Krishna… by Resiliency Radio
57 min listen
Reading, Writing, and Erasing the Way to Epigenetic Cancer Therapies: Targeting the epigenome—the regulators that turn on and off the activity of genes—has long been viewed as a promising way to treat cancer. But despite the promise of this approach, early efforts brought few successes in part because of the broad effe... by The Bio Report
24 min listen
Pioneering Antiviral Conjugates with Cidara's Dr. Jeff Stein by Business Of Biotech
38 min listen
Extrachromosomal circular DNA, chromosome evolution & circular DNA in human disease with the Regenberg Lab (Dr Birgitte Regenberg and Dr Sam Keating) by The Genomics Lab
71 min listen
Bonus Sample: JP Sears’s Woke CBD Grift by Conspirituality
6 min listen
Episode 40: Exploring Developability Concepts with Bispecific Antibodies by The Chain: Protein Engineering Podcast
16 min listen
Using CRISPR to Target RNA Instead of DNA: The gene editing technology CRISPR-Cas9 is being harnessed to alter DNA, but Locanabio is using it to create a new class of genetic medicines that can precisely target and modify dysfunctional RNA. The company says that its approach will allow it to ... by The Bio Report
20 min listen
Zombie Cells / Cellular Senescence with Dr. Greg Kelly by Longevity Optimization with Kayla Barnes-Lentz
44 min listen
Reed Kelso Strives to Enable CRISPR Access For All Scientists: Reed Kelso, Head of Cell Engineering Research and Applications at Synthego, is a bio-wizard. In this episode, Kevin & Minu catch up with Reed about his role at Synthego and the day-to-day operations at the fast paced start-up. Reed talks about the revolu... by CRISPR Cuts
16 min listen
Episode 25: A Between the Biotech Waves conversation with Rodolphe Barrangou, the Todd R Klaenhammer Distinguished Professor at NC State University. by Between the Biotech Waves
60 min listen
Episode 24: Taking Risks and Setting Precedent in Bioanalytical Assays for Cell & Gene Therapies by The Chain: Protein Engineering Podcast
28 min listen
Have we reached a turning point with migraine medication?: Could a new class of drugs change the lives of those living with migraine? by The Inquiry
24 min listen
1107. Update: Study to Investigate the Safety of the Transplantation of Human Glial Restricted Progenitor Cells into Patients with Transverse Myelitis by Ask the Expert
18 min listen
PP# 83: Your Gut Microbiome & Your Vaginal Health with Kiran Krishnan: Kiran Krishnan is a Research Microbiologist and microbiome expert. Kiran is currently involved in 7 novel human clinical trials on probiotics and the human microbiome and has extensive knowledge of the latest science on the human microbiome as it... by The Period Party
37 min listen
Gene-y in a Bottle: ENCORE You can’t pick your parents. But soon you may be able to change the DNA they gave you. CRISPR technology is poised to take DNA editing to new levels of precision and speed. Imagine deleting genes from your body that... by Big Picture Science
54 min listen
EP 13: Stem cells and Brain Therapies with Regan Archibald, LAc: Tune in for this lively discussion with Regan Archibald as we discuss the future of medicine, Stem cells, and brain therapies. Regan is considered an expert in the field of regenerative stem cell therapy and lectures on this topic extensively.... by What the Health?! with Dr. Greg Eckel
56 min listen
Understanding Meningioma Biology: Abrar Choudhury: Meningioma is the most common intracranial tumor, with limited treatment options. In order to identify new therapies for meningioma, it is important to understand their underlying biology. In this Share Your Research talk, Dr. by iBiology Podcast
23 min listen
Understanding Meningioma Biology: Abrar Choudhury: Meningioma is the most common intracranial tumor, with limited treatment options. In order to identify new therapies for meningioma, it is important to understand their underlying biology. In this Share Your Research talk, Dr. by iBiology Videos
23 min listen
The science and ethics of rewriting our DNA | Jennifer Doudna: Biochemist Jennifer Doudna won the 2020 Nobel Prize in Chemistry for pioneering CRISPR, a revolutionary biotech tool that can edit DNA with unprecedented precision and ease. But how exactly does CRISPR work, and what consequences may arise from altering our internal makeup? by The TED Interview
46 min listen
Gene Editing Nature: Gene editing could revolutionise environmental conservation – but should we use it? by Costing the Earth
29 min listen
Genome Integrity: Dr Opher Gileadi tells us how cells maintain genome integrity and how we can use it in our fight against cancer. by Cancer
6 min listen
NEJM Interview: Dr. Beau Kilmer on the effects of cannabis on health and how jurisdictions can minimize harms related to its legalization. by NEJM Interviews
9 min listen
Company Overview: Greenwich LifeSciences (GLSI) by Schwab Network
7 min listen
The Benefits Of Sound Therapy | How To Optimize Your Nervous System Health by Finding Genius Podcast
35 min listen
What Is The Science of Change? by The Science of Change
2 min listen
Is This Glycoprotein Responsible For The Autoimmune Effects of Red Meat by Super Human Radio
81 min listen

Discover this podcast and so much more

Christian Groendahl On Pioneering a CRISPR-based Microbial Gene Therapy

Christian Groendahl On Pioneering a CRISPR-based Microbial Gene Therapy

Description

Titles in the series (32)

More Episodes from CRISPR Cuts

Related podcast episodes