In this episode of SurgOnc Today, Ajay Maker, MD, Director of Surgical Oncology at AIMMC/Creticos Cancer Center at the University of Illinois at Chicago, interviews SSO Gastrointestinal Disease Site Work Group members about the most influential papers in GI surgical oncology from 2019. Four conversations cover topics including: A recent Lancet study about combination chemotherapy for pancreatic cancer Advanced gastric cancer and perioperative chemotherapy regimens New therapies for metastatic gastric cancer An Annals of Surgical Oncology paper about diagnosing GI cancers from circulating tumor DNA Ajay Maker, MD, is the Director of Surgical Oncology at AIMMC/Creticos Cancer Center, and Associate Professor in the Department of Surgery, Division of Surgical Oncology at the University of Illinois at Chicago Evan S. Glazer, MD, PhD, is Assistant Professor of Surgery  and Principal Investigator, Center for Cancer Research at the University of Tennessee Health Science Center Yanghee Woo, MD, is Director, Gastroenterology Minimally Invasive Therapy Program and Associate Clinical Professor, Division of Surgical Oncology, Department of Surgery at City of Hope Mio Kitano, MD, is Assistant Professor in the Division of Surgical Oncology and Endocrine Surgery at the University of Texas Health San Antonio Carlos Chan, MD, PhD, is Assistant Professor of Surgery, Director-Molecular Epidemiology Resource Core, Assistant Professor of Radiation Oncology, Assistant Professor of Surgery, Surgical Oncology and Endocrine Surgery at the University of Iowa