Does in utero exposure to anti-seizure medication affect motor and mental development? A study using data from the Kerala Registry of Epilepsy in Pregnancy included more than 1,300 infants. Those exposed to valproate monotherapy, as well as any polytherapy, had higher risks of developmental delay.Dr. Bruna Nucera talked with Dr. Sanjeev Thomas about the findings and implications of the study.The study, Differential impact of antenatal exposure to antiseizure medications on motor and mental development in infants of women with epilepsy, was published in Epileptic Disorders in June 2022.Other publications from the Kerala Register of Epilepsy in PregnancyOther epilepsy pregnancy registries:Australian Register EURAP North American Pregnancy RegistryUK RegisterThis episode was reported by Dr. Bruna Nucera, and edited and produced by Nancy Volkers.Sharp Waves content is meant for informational purposes only and not as medical or clinical advice.  Support the showSharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, Twitter, and Instagram.