Full interview with Marissa Bello PhD and Darryn Willoughby PhD FISSN3:10 – The lowdown on rep ranges; do you need high loads for hypertrophy7:05 – Dr Willoughby thinks this focus on sets and reps is a bit convoluted. There’s much more to it than that.  7:47 – These acute bout studies barely tell a story; nobody trains that way anyhow10:05 – The need or utility of doing reps to failure14:27 – Compound vs isolation movements; effect on skeletal muscle hypertrophy. 23:20 – Periodization question: all phases produce hypertrophy. Why is there only one phase called “hypertrophy.” Why periodization often can’t be used in sports.27:45 – So many training studies. But nobody trains that way! Is there a value to these studies? Even a little bit?35:15 – The acute changes in plasma T and cortisol.  Any relevance to training adaptations?43:30 -  T boosters – these little blips in plasma T – a scam or what?47:46 – SARMs – selective androgen receptor modulators – useful or not?51:10 – Sex and age differences in the training response vis a vis hypertrophy58:36 – Sarcoplasmic hypertrophy?Our special guestsDr. Marissa Bello PhD, CSCS*D is a current visiting instructor at the University of Alabama at Birmingham. She graduated from her undergraduate in biology at Brandeis University while competing in soccer all four years. She then completed her Masters at Rutgers University, where her main focus was supplementation and sports performance. While at Rutgers she worked closely with the athletic department and incorporating athlete monitoring with several teams. Her PhD was completed at Mississippi State University in Exercise Physiology with a minor in nutrition. Her dissertation research focused on optimizing performance and training adaptations. Her research interests include sports performance, nutrition, endocrinology, and physiological adaptations.Dr. Willoughby holds B.S. and M.Ed. degrees in Exercise Science from Tarleton State University and a Ph.D. in Exercise Physiology with sub-emphases in Nutritional Biochemistry and Molecular Biology from Texas A&M University. He also possesses a graduate clinical certificate in Clinical Anatomy. Dr. Willoughby is a Fellow of the American College of Sports Medicine (ACSM), International Society of Sport Nutrition (ISSN), American College of Nutrition (ACN), and American Society of Exercise Physiologists (ASEP). He is a Certified Strength and Conditioning Specialist through the National Strength and Conditioning Association, a Certified Sports Nutritionist through ISSN, and a Certified Exercise Physiologist through ASEP. He is also a Past-President of the ISSN. He has also been presented with the Lifetime Achievement Award by the Society of Weight Training Injury Specialists (SWIS). Dr. Willoughby has over 150 publications in high-tier scientific peer-reviewed research journals and is considered a pioneer in the field of exercise science.Email: SportsScienceDudes@gmail.com BIO: Jose Antonio PhD earned his doctorate and completed a postdoctoral research fellowship at the University of Texas Southwestern Medical Center. He is a co-founder and CEO of the ISSN (www.issn.net), and co-founder of the Society for NeuroSports (www.neurosports.net). He is Professor of Exercise and Sport Science at Nova Southeastern University. Twitter: @JoseAntonioPhD Instagram: supphd and the_issn BIO: Anthony Ricci Tony Ricci is a Professor in the Departments of Human Performance, and Psychology and Neuroscience at Nova Southeastern University. Tony holds Master’s Degrees in Sport Science and Human Nutrition and a Doctorate in Sport Psychology and Psychomotor Learning. Twitter: @sportsci_psyDoc Instagram: @sportsci_psyDoc