"depression is a mental state of low mood there are several subtypes of depression but the major depressive disorder is the one that is usually intended it is expected to be the number one cause of disease burden worldwide by 2030 the term major depressive disorder was first used in the 1970s and the disorder was added to the diagnostic and statistical Manual of mental disorders known as the DSM in the in 80s today we have the DSM-5 which lays out nine criteria on which the diagnosis is based they include a low mood most of the day on most days and anhedonia which means a loss of pleasure or interest in previously enjoyable activities these two are considered core symptoms and one of them must be present for a diagnosis of major depressive disorder the other criteria include significant weight loss or weight gain insomnia or hypersomnia meaning not sleeping enough or sleeping too much fatigue or a loss of energy nearly every day psychomotor retardation which means ass going down of thoughts and physical movements that is noticed by others then there is inappropriate guilt or feeling worthless a reduction in the ability tea to concentrate and it recurrent thoughts of death a total of five or more over a period of at least two weeks leading to significant clinical distress or impaired functioning need to be present for the diagnosis and the symptoms cannot be the result of substance abuse or another condition major depressive disorder is thought..."
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