Conference clinical cochair Diane Havlir, MD, a professor of medicine at the University of California, San Francisco, sits down with JAMA Deputy Editor Preeti Malani, MD, MSJ, about research highlights presented at the 30th annual CROI, held in Seattle. The infectious disease experts discuss postexposure prophylaxis for sexually transmitted infections, a new protease inhibitor for COVID-19, goals for preventing HIV transmission, and more. Related Content: Highlights From CROI, the Conference on Retroviruses and Opportunistic Infections—Postexposure Prophylaxis for Sexually Transmitted Infections, a New Protease Inhibitor for COVID-19, Goals for Preventing HIV Transmission, and More