Podcast 299: Lung cancer and atezolizumab — results from the IMpower010 trial

Podcast 272: And now for something completely different… almost: Dr. Paul Sax writes the closest thing that the NEJM Group has to humor. He’s serious, of course, since his blog “HIV and ID Observations” concerns all things infectious . But he sprinkles in the odd cartoon or links to … dog videos, by Clinical Conversations

10 min listen

Podcast 276: Pay attention to the structural barriers that contribute to clinical inequity — Karol Watson: In this, our second conversation on race and clinical equity, Dr. Karol Watson of UCLA offers her observations on what she’s observed as a cardiologist trying to deal with treatment plans for patients who’ve lost their health insurance or have had to g... by Clinical Conversations

11 min listen

Podcast 275: Race and Clinical Equity — a Conversation with Dr. Kimberly Manning: We’ve conducted a set of four interviews with physicians on the topic of race and clinical equity. The conversations center not so much on their published research, but on the roles that these physicians take in their organizations and, in addition, by Clinical Conversations

20 min listen

Podcast 273: The journals and the pandemic — NEJM: Eric Rubin is editor-in-chief of the New England Journal of Medicine. I asked him how COVID-19 has affected that journal, which has been around since the War of 1812 and seen its share of pandemics. Listen in — it’s the first in a planned series of int... by Clinical Conversations

19 min listen

Podcast 274: Preliminary Thoughts on the 2021 ASCO Gastrointestinal Cancer Conference: Apologies for the long silence. We have been off doing other things — one of which has been figuring out how to cover conferences. Last month, after much preparation, we covered the American Society of Hematology (ASH) annual conference; our second for... by Clinical Conversations

19 min listen

Podcast 277: Race and clinical equity — know your patients — a conversation with Karen Dorsey Sheares: Dr. Sheares talks about her experience with inequities. She believes that clinicians should aspire to be students of their patients as well as of the pathophysiology of the diseases their patients present with. Listen in. Running time: 20 minutes by Clinical Conversations

21 min listen

Podcast 278: Where equity and community health intersect — a conversation with Joseph Betancourt: An internist at Massachusetts General Hospital, Dr. Joseph Betancourt also runs their program on equity and community health. In this, the final entry in our four-interview exploration of race and clinical equity, by Clinical Conversations

17 min listen

Podcast 284: The clinical situation in Ukraine: Some 85 years ago Guernica was bombed, and after that came Dresden, Coventry, Hiroshima, Bach Mai, and the rest. This episode of Clinical Conversations asks how it might be possible to help clinicians under bombardment in Ukraine. As you will hear, by Clinical Conversations

20 min listen

Podcast 280: MIS-C after Covid-19 in adolescents — can vaccination prevent it?: Multisystem inflammatory syndrome in children (or MIS-C) is a serious complication of Covid-19 infection, usually showing up about a month after infection. CDC worked with several hospitals around the U.S. to discern whether vaccination in adolescents ... by Clinical Conversations

16 min listen

Podcast 279: Age-specific data do better than age-adjusted data in revealing health inequities: Kiarri Kershaw has written a simple letter in JACC — the Journal of the American College of Cardiology. The letter conveys a strong message: health inequities don’t act uniformly across one’s lifetime. Her examination of Black versus white mortality fr... by Clinical Conversations

6 min listen

Podcast 282: Vaccination after Covid-19 recovery prolongs natural immunity to reinfection: Governments’ directives about how and when to vaccinate people who’ve recovered from Covid-19 vary widely. But, according to this episode’s guest, Dr. Ronen Arbel, they all say they don’t have enough evidence to set firm policy. So, by Clinical Conversations

15 min listen

Podcast 283: More data — this time from the U.K. — about post-Covid vaccination: You want more evidence that post-recovery vaccination against Covid-19 reinfection helps? Here is a careful study from the U.K. that followed some 35,000 health care workers — initially without symptoms — in over 100 institutions there. by Clinical Conversations

11 min listen

Podcast 281: Drug Costs — What’s “The Right Price” for prescription pharmaceuticals?: Why can’t the U.S. control prescription drug pricing as they do in the U.K., where per-capita spending is less than half our level? In a capitalist democracy, many parties — the drug companies, medical associations, by Clinical Conversations

26 min listen

Podcast 285: GERD’s revised guidelines — an internist and a gastroenterologist discuss them.: Gastroesophageal reflux, or GERD, was the focus of a revised set of guidelines issued in January in the American Journal of Gastroenterology. Given the frequency of that condition in primary care clinics, internist and NEJM Journal Watch editor-in-chie... by Clinical Conversations

24 min listen

Podcast 286: Talking about addiction treatment by candlelight from Ukraine’s Donetsk region: Dr. Natalia Shevchuk (pictured above) treats substance use disorders in Ukraine’s Donetsk region. Her face is candlelit because her town is under curfew, and people aren’t allowed to put on their room lights (if they have electricity) in the hours of d... by Clinical Conversations

19 min listen

Podcast 293: HER2-“low” breast cancer and its reponse to an antibody-drug conjugate: Patients with metastatic breast cancer whose tumors express low levels of HER2 are generally classified and treated as having HER2-negative disease. However, Dr. Shanu Modi of the Memorial Sloan Kettering Cancer Center and a group of international coll... by Clinical Conversations

11 min listen

Podcast 288: Following up with a Ukrainian narcologist: Spend 15 minutes with Dr. Natalia Shevchuk, whom we interviewed by candlelight last month. She is sheltering in the Odessa region now, having left the Donetsk area. This time, she relates how she lost a colleague in Russia’s attack on the Kramatorsk ra... by Clinical Conversations

15 min listen

Podcast 291: Unionized nursing homes had lower mortality during Covid-19: In the early waves of the Covid-19 pandemic why did patients in unionized nursing homes, have a roughly 10% lower rate of mortality than those in non-unionized ones? A report in Health Affairs tries to sort out the possible reasons. by Clinical Conversations

13 min listen

Podcast 287: Thinking about quality-of-life in migraine by Clinical Conversations

14 min listen

Podcast 290: USPSTF’s new take on aspirin and primary prevention of CVD: The U.S. Preventive Services Task Force recently issued its sixth set of guidelines on using daily aspirin to prevent cardiovascular disease. The guidelines appeared in JAMA — whose editors asked our guest, Dr. Allan Brett, by Clinical Conversations

15 min listen

Podcast 289: Saline versus balanced crystalloids — what to choose: Saline or balanced crystalloids? The question of which resuscitation fluid to use in clinical practice seems to have been settled by recent research findings — or at least settled in favor of balanced crystalloids. But wait, by Clinical Conversations

16 min listen

Podcast 292: Informed consent and apnea testing for death — or — What is death, anyway?: Apnea testing is part of the protocol used to determine whether a patient is dead according to neurologic criteria. The question is, do clinicians need to obtain consent to proceed? In a fascinating 15-minute chat, two intensivists, Drs. by Clinical Conversations

15 min listen

Podcast 297: Forget about all that vitamin D testing!!: A VIDEO RECORDING OF THIS INTERVIEW IS AVAILABLE HERE. THE USUAL AUDIO FILE IS AVAILABLE BELOW Steven Cummings has co-written a take-no-prisoners editorial in the New England Journal of Medicine. The topic? Vitamin D supplements. The conclusion? by Clinical Conversations

13 min listen

Podcast 294: PD-1 blockade in locally advanced rectal cancer by Clinical Conversations

13 min listen

Podcast 295: How should clinicians manage severe (but asymptomatic) carotid artery stenosis while awaiting CREST-2’s results?: CREST-2’s results are probably more than a year away. In the meantime, what to do about diagnosed severe (but asymptomatic) carotid stenosis? Recent results suggest that medical management compares favorably with the surgical approach. by Clinical Conversations

16 min listen

Podcast 296: A roundtable on the question, Why are young internists flocking to the hospitalist practice style?: A VIDEO RECORDING OF THIS ROUNDTABLE IS AVAILABLE CLICK HERE. THE USUAL AUDIO FILE IS AVAILABLE BELOW Your host is old enough to remember when hospital corridors featured physicians with little black bags, scurrying around to see their patients. by Clinical Conversations

30 min listen

Podcast 301: Monkeypox — what to look for, how to treat: A VIDEO RECORDING OF THIS INTERVIEW IS AVAILABLE HERE. This time, we look to New York for guidance on recognizing and treating monkeypox. Dr. Eric Meyerowitz of Montefiore and Dr. Stephen Baum of Einstein will lead you through the monkeypox thicket in ... by Clinical Conversations

17 min listen

Podcast 300: NADIM II trial offers “quite exciting” results in lung cancer: A VIDEO RECORDING OF THIS INTERVIEW IS AVAILABLE HERE. We’re back with another interview from this year’s IASLC conference. This time, Christine Sadlowski and Dr. Julia Rotow interview Dr. Mariano Provencio about the survival outcomes from the NADIM II... by Clinical Conversations

10 min listen

Podcast 299: Lung cancer and atezolizumab — results from the IMpower010 trial: A VIDEO RECORDING OF THIS INTERVIEW IS AVAILABLE HERE. Interim results on overall survival in phase 3 of the IMpower010 trial were presented at this year’s meeting of the International Assosciation for the Study of Lung Cancer (IASLC). by Clinical Conversations

15 min listen

Podcast 298: COPD exacerbations — 7 days of antibiotics versus 2: A VIDEO RECORDING OF THIS INTERVIEW IS AVAILABLE AT THIS LINK. In treating most exacerbations of chronic obstructive pulmonary disease (COPD) the usual regimen consists of prednisone plus 5- to 7-days of antibiotics. by Clinical Conversations

14 min listen

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Podcast 299: Lung cancer and atezolizumab — results from the IMpower010 trial

Podcast 299: Lung cancer and atezolizumab — results from the IMpower010 trial

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