There are so many types of germs that cause illness, but so little we know about them. Terence Dermody, MD, physician-in-chief and scientific director at UPMC Children’s Hospital of Pittsburgh, is motivated by the endless opportunities in Infectious Diseases to discover more about these little mysteries that affect our patients. Hosts Carolyn Coyne, PhD, and Brian Martin, DMD, ask Dr. Dermody about what drew him to Virology and Infectious Diseases and how he balances his research and clinical work. Dr. Dermody also introduces the Pittsburgh Study, a multi-year longitudinal population study that aims to follow children in Allegheny County from birth to completion of high school to answer the question: What determines health?