In this podcast, Dr. Sharon Straus and Prof. Monika Kastner share the results of their research on effectiveness of interventions for managing multiple high-burden chronic diseases affecting older adults. They discuss whether the single-disease approach to management is better than an integrated multi-disease approach to care.Prof. Monika Kastner is Research Chair in Knowledge Translation and Implementation at North York General Hospital in Toronto and Dr. Sharon Straus is interim physician-in-chief at St. Michael’s Hospital and vice chair and professor of medicine at the University of Toronto.Full research article: www.cmaj.ca/lookup/doi/10.1503/cmaj.171391To request a transcript of this podcast, contact cmajgroup@cmaj.caSubscribe to CMAJ Podcasts on Apple Podcasts or your favourite podcast app. You can also follow us directly on our SoundCloud page or you can visit www.cmaj.ca/page/multimedia/podcasts.