We are all familiar with what it feels like to react to a stressful or threatening event. That uneasy feeling of worry or panic, coupled with an increased heart rate, rapid breathing and loss of hunger, is a typical physiological response known as ‘fight or flight’. Of course, once the perceived threat goes away, so too should this reaction, and we soon after expect to return to a normal and relaxed state. However, for a considerable number of people, that uncomfortable feeling of fear or impending danger can be a persistent presence and so too can those distressing physiological symptoms. It is an unfortunate feature of the 21st Century that anxiety disorders are the most common psychiatric presentation in Australia, affecting one in seven people.In part 2 of our interview with Dr Jerome Sarris, we explore some truly exciting nutraceutical and herbal therapy developments that may contribute a substantial piece of the anxiety treatment puzzle.