Have you ever heard of endolysins? Are you wondering what these things are and how are they relevant when talking about skin conditions? Today’s episode is sponsored by Gladskin which makes a topical cream that I think you should know about called Eczema Cream with Micreobalance®… and it’s highly relevant to what we’re talking about today. I became aware of Gladskin several years ago when community members started to share their personal stories of how Gladskin’s Eczema Cream had helped their eczema flares + symptoms.Because I didn’t fully understand how exactly the product worked, I read up on the Micreobalance® endolysin technology and talked to people at Gladskin so that I better understood why it could be helpful while being free of antibiotics and steroids. I was really impressed with how neat endolysins are – sort of like pac-mans (for those of you who are old enough to remember that video game) that target the bad and preserve the good, to keep your skin microbiome in check. You can check out more about Gladskin Eczema Cream with Micreobalance® AND save 15% off your order at www.gladskin.com/healthyskinshow. My guest today is Dr. Peter Lio, a Clinical Assistant Professor of Dermatology & Pediatrics at Northwestern University Feinberg School of Medicine. He received his medical degree from Harvard Medical School, completed his internship in Pediatrics at Boston Children’s Hospital, and his Dermatology training at Harvard where he served as Chief Resident in Dermatology. While at Harvard, he received formal training in acupuncture. Dr. Lio will be giving you the low down on endolysins – I know you’re going to find this just as fascinating as I do, so let’s dive in! Have you ever tried Gladskin, and has it helped on your skin journey? Post something you learned it in the comments! In this episode: The difference between the skin microbiome of eczema vs healthy skin Thoughts on antibiotic resistance as a growing medical concern Endolysins: what are they + how they support the skin microbiome How Gladskin's Micreobalance® utilizes endolysins to help the skin's microbiome Real-life stories from Dr. Lio's practice of patients using Gladskin Tips + strategies to help you use Gladskin with Micreobalance® Quotes “There is some very convincing evidence that it may help with not only the bacterial balance on the skin, but also with atopic dermatitis. So we can actually see some of the studies are studied in patients with eczema or atopic dermatitis. I think there is pretty convincing evidence of clinical helpfulness of these [endolysin] products.” [10:47] “... the baby's branded one. Actually, they remove the oat because there is some discussion around putting foods on our skin and the connection between allergy. Some people really do have an oat allergy. So [The Eczema Cream for Babies and Kids] is an even simpler, kind of an even cleaner preparation for the babies, which I love." [14:44] "I'm really excited about Gladskin's work in this space. I think they're being bold. They're trying something totally new and entering in as really the only one of its kind right now. So it's kind of exciting to have a totally new class. When patients say, 'What is this like?' It's like, 'Nothing. It's really a totally new thing!' This is something really new and exciting." [22:46] Links Check out Gladskin here Follow Gladskin on Instagram | Facebook | Twitter Find Dr. Lio Online Healthy Skin Show ep. 001: How to Protect & Strengthen Your Skin Barrier w/ Dr. Peter Lio Healthy Skin Show ep. 176: Dealing With Recurrent Skin Infections w/ Dr. Peter Lio Follow Dr. Lio on Twitter | Facebook Research The Advantages and Challenges of Using Endolysins in a Clinical Setting (Viruses, 2021) Topical S. aureus-Targeting Endolysin Significantly Improves Symptoms and QoL in Individuals With Atopic Dermatitis (Journal of Drugs in Dermatology, 2021) Endolysins as Antimicrobials (Advances in Virus Research, 2012) Targeted anti-staphylococcal therapy with endoly