E13: Withdrawing HCQ in SLE

FromThe Evidence Based Rheumatology Podcast

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E13: Withdrawing HCQ in SLE

FromThe Evidence Based Rheumatology Podcast

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Length:

11 minutes

Released:

Mar 18, 2018

Format:

Podcast episode

Description

Short podcast today on an old RCT addressing the utility of hydroxychloroquine (plaquenil) in lupus. It's an oldie but goodie and one that I enjoyed talking about.

Released:

Mar 18, 2018

Format:

Podcast episode

Titles in the series (87)

A weekly podcast for physicians interested in evidence based medicine and rheumatology. Find the papers at ebrheum.com

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E12: ACR 2015 Workforce Study - the Rheumageddon!: This week we'll discuss the recently published ACR Workforce Study, which estimates a substantial deficit in the workforce by 2030. We'll consider how dire the situation actually is - checkout the paper itself here. by The Evidence Based Rheumatology Podcast
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E13: Withdrawing HCQ in SLE: Short podcast today on an old RCT addressing the utility of hydroxychloroquine (plaquenil) in lupus. It's an oldie but goodie and one that I enjoyed talking about. by The Evidence Based Rheumatology Podcast
11 min listen
E16: Tocilizumab in Giant-Cell Arteritis - GIACTA: Getting back to our usual format, this week we'll discuss the GIACTA trial, which compared various schedules of tocilizumab to various schedules of placebo and prednisone. It's an important trial that has changed the face of GCA and will be a refreshing... by The Evidence Based Rheumatology Podcast
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14 min listen
E19: Clinical Utility of a Positive ANA: Quick podcast this week on the utility of an ANA. It's a frequent reason for referral (17% in this series) to rheumatology offices and this is a useful paper for context. Find the paper itself here. by The Evidence Based Rheumatology Podcast
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E36: Baricitinib for SLE: This week I discuss the phase 2 trial on baricitinib in SLE. Though it's early times (and the total flop of rituxan in ME/CFS recently can attest to this), this was a large phase 2 and I'm hopeful it carries through to the ongoing phase 3 trials. Follo... by The Evidence Based Rheumatology Podcast
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E7: The ALMS Trial - MMF vs CYC for Lupus Nephritis: Today we'll be discussing the ALMS trial, which pitted cellcept against cyclophosphamide. It's a good trial that has had profound influences on our practice and well worth a read. Access the paper itself here. by The Evidence Based Rheumatology Podcast
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E17: Steroids and the Risk of Scleroderma Renal Crisis: Short but impactful paper this week on the association between steroids and scleroderma renal crisis. Find the original paper here. by The Evidence Based Rheumatology Podcast
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E23: Stress Related Disorders and Subsequent Autoimmune Disease: Great article this week on stress related disorders and their relationship with subsequent autoimmune disease. One of my favorite recent papers from my least favorite way to do a study! Remember, all my articles can be found here! by The Evidence Based Rheumatology Podcast
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E8: Mepolizumab or Placebo for EGPA: This week we'll discuss a recent trial on mepolizumab - and IL-5 inhibitor - for eosinophilic granulomatosis with polyangiitits. Find the paper here and be sure to follow us on twitter @JBRheum! by The Evidence Based Rheumatology Podcast
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E79: Vasculitis Guidelines E5 - GCA with Dr. Mehrdad Maz: On today's episode I discuss GCA with Dr. Mehrdad Maz. He is the Division Director of the Kansas University Allergy, Clinical Immunology and Rheumatology Section and served on the Steering Core Committee of the ACR-VF Vasculitis Treatment Guidelines. We... by The Evidence Based Rheumatology Podcast
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E28: Nurse Run Treat to Target vs. Usual Care? in Gout: Interesting trial this week pitting an elaborate nurse led group against suboptimal usual care. Suboptimal usual care lost pretty badly, but what to make of this? And does it support the rheumatologist side of the treat to target controversy? Listen t... by The Evidence Based Rheumatology Podcast
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E34: Leggo my Eggo! Eggs, Cholesterol, CVD, Mortality: In this week's episode I depart briefly from discussing papers in the rheumatology literature to dive headfirst into the recent controversy over eggs and cardiovascular disease. Our patients eat eggs too, so I figured it would still be applicable. Please... by The Evidence Based Rheumatology Podcast
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E10: Abatacept in RA-ILD: Quick podcast tonight reflecting the Rheumatology Journal Club (@RheumJC) discussion! I joined as they discussed the use of abatacept in patients with rheumatoid arthritis who develop ILD. It's our first observational trial, so it's ripe for critique! F... by The Evidence Based Rheumatology Podcast
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E15: The Ribosomal P Isn't Useful in NPSLE by The Evidence Based Rheumatology Podcast
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E51: Rheum4Debate - "Start TCZ Upfront in GCA": Rheum4Debate is back! This week we have Dr. Anisha Dua arguing in support of the motion, "Patients with newly diagnosed GCA should start glucocorticoids WITH tocilizumab over glucocorticoids alone." I argue against the motion and Dr. Sarah Fantus was k... by The Evidence Based Rheumatology Podcast
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E45: TNF or TCZ or ABA or RTX: Real World Data for RA: This week I tackle an interesting cohort study that Jack Cush (@RheumNow) mentioned in his podcast. It's a nice opportunity to discuss bDMARDs in the "real world" (AKA Sweden). Follow me @ebrheum and let me know what you think of the episode! by The Evidence Based Rheumatology Podcast
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E42: SENSCIS - Nintedanib for Systemic Sclerosis ILD: This week I'll discuss an important paper in systemic sclerosis, the recent SENSCIS trial that compared 150mg nitedanib to placebo. I wind up coming down pretty hard on this drug; I think it's hype has vastly outpaced its utility. Get the paper itself a... by The Evidence Based Rheumatology Podcast
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E39: MTX for GCA - 3 RCTs and a Case Control Study: This week a nice case control study out of Mayo challenged my own bias against MTX in GCA. This prompted a deep dive into the literature, including 3 RCTs and meta analysis. At the end of the day, I'm more (almost) fully convinced that MTX offers a (me... by The Evidence Based Rheumatology Podcast
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E54: Rheum4Debate - Triple Tx is 1st Line in RA w/No Response to MTX: Happy New Year! This week Dr. Anisha Dua (@anisha_dua) and Dr. Sarah Fantus (@sarahfantus) debate this motion: "In MTX non-responders with RA, triple therapy (adding HCQ & SSZ) should be first line." Please be sure to VOTE AGAIN on twitter (@ebrheum) a... by The Evidence Based Rheumatology Podcast
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E41: Rheum4Debate "SLE Pts. on Cytoxan Should Receive Bactrim": Welcome back! This is the second episode of Rheum4Debate, an oxford-style debate show for the field of rheumatology. In this podcast we'll tackle the question of bactrim prophylaxis in patients receiving cyclophosphamide. The motion was: “Bactrim pro... by The Evidence Based Rheumatology Podcast
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E50: Housekeeping 2: Super brief "checking in" podcast this week. In short, say "hi" at ACR, write me a review on apple podcasts, send this to a friend, and keep listening :). by The Evidence Based Rheumatology Podcast
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E46: Rituximab in Lupus: Finally got around to tackling rituximab in SLE. This is a tough topic: lots of people feel passionately one way or another, flawed observational data supports its use, flawed RCTs did not find significant benefit, and patients are left in the lurch. I... by The Evidence Based Rheumatology Podcast
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E26: Housekeeping 1: Every 25 episodes I'd like to step back and touch base about where the podcast is headed. Thanks to everyone who has been listening! Apologies for nothing exciting or useful this week. by The Evidence Based Rheumatology Podcast
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E43: Tofacitinib for MDA5 Amyopathic Dermatomyositis ILD: Back this week to discuss an interesting paper in the NEJM. Lots of interesting issues, most notably historical controls and their limitations. Find all my work at ebrheum.com! by The Evidence Based Rheumatology Podcast
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E25: MAINRITSAN 2 - Fixed vs. Tailored Rituxan for AAV: Interesting trial this week evaluating a fixed schedule of rituximab vs. a tailored approach to therapy. See you all at ACR this week! by The Evidence Based Rheumatology Podcast
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E13: Withdrawing HCQ in SLE

E13: Withdrawing HCQ in SLE

Description

Titles in the series (87)

More Episodes from The Evidence Based Rheumatology Podcast