Dr. Mike Gilmore is the Sir William Osler Professor of Ophthalmology, and Microbiology and Immunobiology at Harvard Medical School. Dr. Gilmore is the director of the Harvard-wide Program on Antibiotic Resistance, and his research focuses on the evolution and development of multidrug resistant strains of enterococci, staphylococci, and streptococci. The world is facing a serious health crisis with the increasing prevalence of multidrug resistant superbugs; the CDC estimates that there are 2 million infections and 23,000 deaths each year in the U.S. due to antibiotic resistant bacteria. Dr. Gilmore discusses how bacteria become resistant to antibiotics, what scientists are doing to address this problem, and what everyone can do to help alleviate this impending global health crisis. Discussants (in alphabetical order): Dr. Karl Klose (Professor and director of STCEID, UTSA) Dr. Janakiram Seshu (Associate professor, STCEID, UTSA) Dr. Floyd Wormley (Professor, STCEID, UTSA)