Elinor Karlsson, Ph.D., is the director of the Vetebrate Genomics Group at the Broad Institute of MIT and Harvard and (incidentally) my boss. She has a deep knowledge about both population genetics and what we call "complex trait genomics," or the genetics of hard to pin down things like risk of developing cancer or a behavior problem. Elinor talked with me about a recent paper that looked for genetic variants associated with diseases in a large number of dogs from many breeds and mixes. She discusses what this paper found and some ways to intepret those findings. The paper is Donner, Jonas, et al. "Frequency and distribution of 152 genetic disease variants in over 100,000 mixed breed and purebred dogs." PLoS genetics 14.4 (2018): e1007361. https://journals.plos.org/plosgenetics/article?rev=2&id=10.1371/journal.pgen.1007361.
Elinor also discusses a paper about genetic testing that she published recently, and that paper is Moses, Lisa, Steve Niemi, and Elinor Karlsson. "Pet genomics medicine runs wild." (2018): 470-472 https://www.nature.com/articles/d41586-018-05771-0.
Find this episode's transcript here.