19 min listen
Pink sporadic RCCs associated with TSC/MTOR alterations
FromModPath Chat
ratings:
Length:
19 minutes
Released:
May 31, 2022
Format:
Podcast episode
Description
While AML and cysts are the most common renal manifestations in patients with inherited TSC syndromes, approximately 4% will develop renal cell carcinoma (RCC). These include RCC with clear cytoplasm, papillary architecture, and prominent smooth muscle stroma; RCC with granular eosinophilic cytoplasm and macrocystic architecture; and RCC resembling the eosinophilic variant of chromophobe RCC. In recent years and in five studies in the March 2022 issue of Modern Pathology, sporadic counterparts to the hereditary tuberous sclerosis complex-associated RCC that are associated with somatic TSC/MTOR pathway mutations have now been described. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.
Released:
May 31, 2022
Format:
Podcast episode
Titles in the series (58)
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