Sickle Cell Saviors

FromI AM BIO

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Sickle Cell Saviors

FromI AM BIO

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Length:

62 minutes

Released:

Apr 3, 2020

Format:

Podcast episode

Description

Need a dose of inspiration in a time of national tragedy? A remarkable biotech breakthrough from Global Blood Therapeutics offers fresh hope to patients living with sickle-cell disease.

Hosted by Jim Greenwood.

Released:

Apr 3, 2020

Format:

Podcast episode

Titles in the series (100)

Powerful stories of biotechnology breakthroughs, the people they help, and the global problems they solve. Hosted by BIO President & CEO Dr. Michelle McMurry-Heath.

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Going Viral: Vir Biotechnology CEO George Scangos is the scientist selected by his peers to lead the biotechnology industry’s efforts to mitigate and ultimately end the pandemic. He explains how and why the novel coronavirus is so contagious and potentially dangerous to millions. Hosted by Jim Greenwood. by I AM BIO
23 min listen
Biotech’s Finest Hour: As the world waits for biotechnology to deliver COVID-19 treatments and a vaccine, Ambassador Deborah Birx tells BIO’s scientists: “Expectations are high because you’ve delivered for us before and I know that you can deliver for us again.” BIO chairman Jeremy Levin, a biotech pioneer, explains how the industry will rise to meet this moment. Hosted by Jim Greenwood. by I AM BIO
53 min listen
An Alternative to Flying Dirty: While Swedish climate activist Greta Thunberg has kindled a global dialogue about the ravages of climate change and the role of airline emissions, a Colorado biotech is putting forward a jaw-dropping alternative to flight shaming: actual jet fuel with no carbon footprint. Hosted by Jim Greenwood. by I AM BIO
40 min listen
COVID X-FACTOR: The diversity of our adaptive immune system is why people are reacting so differently to the novel coronavirus. No two people present the virus the exact same way to their immune systems. We’ve evolved in this way as humans to ensure no virus can eradicate our species. Hosted by Jim Greenwood. by I AM BIO
32 min listen
Cancer in the COVID Era: Overcrowded hospitals during the pandemic can pose treatment challenges for patients with other serious illnesses. As Kite Pharma CEO Christi Shaw says, “Cancer doesn’t stop in a crisis.” Neither do her company’s employees, who go to extraordinary lengths to get personalized CAR-T treatments to patients around the world. Hosted by Jim Greenwood. by I AM BIO
20 min listen
COVID-19 Could Generate 1st Computerized Vaccine: Futuristic biotech Moderna is the first to clinically test a coronavirus vaccine, created in weeks using only the virus’ genetic code. The company’s messenger RNA breakthrough may be just in time as a former CDC director warns that animal viruses spilling over to humans is the new normal. Hosted by Jim Greenwood. by I AM BIO
60 min listen
First Dose: One day before 16-year-old Izzy Thorpe-Wall takes her first dose of Vertex’s stunning Cystic Fibrosis breakthrough, Thorpe and her mother, Clare, open up about their emotional journey and one brave girl’s determination to stay healthy long enough to meet this day of her dreams. Hosted by Jim Greenwood. by I AM BIO
43 min listen
COVID & the Plastics Problem: Fear and misinformation about how the coronavirus is transmitted has led to dangerous backsliding in society’s efforts to address plastic pollution. But we don’t have to lose this battle to win the COVID war. A Georgia biotech is first to market with a green biopolymer material that looks and feels like plastic but dissolves in ocean water. Hosted by Jim Greenwood. by I AM BIO
32 min listen
Trying our Patients: As genetic sequencing gives scientists new tools to hone in on medical mysteries, Washington politicians flirt dangerously with policies that would stymie the genomic revolution while giving patients scant pricing relief at the pharmacy counter. Hosted by Jim Greenwood. by I AM BIO
36 min listen
Biotech's Finest Hour (Redux): As the world waits for biotechnology to deliver COVID-19 treatments and a vaccine, Ambassador Deborah Birx tells BIO’s scientists: “Expectations are high because you’ve delivered for us before and I know that you can deliver for us again.” BIO chairman Jeremy Levin, a biotech pioneer, explains how the industry will rise to meet this moment. Hosted by Jim Greenwood. by I AM BIO
48 min listen
COVID’s Essential Work: The physician-wife of Roivant Sciences CEO Vivek Ramaswamy rushed back to the front lines at the pandemic’s peak — less than a month after giving birth to the couple’s first son. Meanwhile, dad cared for their newborn while testing a promising therapeutic that seeks to overcome deadly cytokine storms caused by the novel coronavirus. Hosted by Jim Greenwood. by I AM BIO
30 min listen
“Herd” Immunity: Biotech companies are working feverishly to develop antibody therapies to provide short-term protection against COVID-19. But what if the novel coronavirus mutates and outwits traditional monoclonal antibodies? Well, that’s where the super cows come in. Hosted by Jim Greenwood. by I AM BIO
36 min listen
Coronavirus Lung Treatment Could be Ready In Weeks: Regeneron’s rheumatoid arthritis drug shows promise to treat coronavirus-related lung syndrome and stop the inflammation that leads to death. The company also expects to test a preventative antibody shot in June. Hosted by Jim Greenwood. by I AM BIO
40 min listen
Superbuggin’: Incurable gonorrhea and the deadly hospital superbug C. diff offer a frightening window into the gathering public health menace of antibiotic resistance. If society doesn’t wake up and tackle the problem, we could be headed toward a calamity on the magnitude of climate change. Hosted by Jim Greenwood. by I AM BIO
28 min listen
The Other Pandemic: Beating “Nightmare Bugs” (Part 2 of 2): Viral pandemics can lead to secondary bacterial infections that kill millions, Dr. Anthony Fauci concluded after studying the 1918 Spanish flu. A century later, COVID and antibiotic resistance are proving to be a lethal combination. What are the biopharma industry and Congress doing to keep your loved ones safe from superbugs? Hosted by Jim Greenwood. by I AM BIO
32 min listen
What Can Iceland Tell Us About COVID?: The people of Iceland — a country of 360,000 — eagerly volunteered for genetic research on how the coronavirus affects a homogeneous population. Amgen’s work in the Land of Fire and here at home could deliver answers and antibodies to help mitigate the pandemic threat. Hosted by Jim Greenwood. by I AM BIO
32 min listen
Deep Diving for COVID Cures: By studying our earliest evolutionary ancestors in the ocean, marine biotech researchers are gaining fresh insights about everything from anti-virals to coronavirus nasal swab testing to the inner workings of our adaptive immune systems. Learn what sea sponges, lugworms and sharks can teach us about improving human health during this crisis. Hosted by Jim Greenwood. by I AM BIO
43 min listen
Sickle Cell Saviors: Need a dose of inspiration in a time of national tragedy? A remarkable biotech breakthrough from Global Blood Therapeutics offers fresh hope to patients living with sickle-cell disease. Hosted by Jim Greenwood. by I AM BIO
62 min listen
The Other Pandemic “Bugs Always Win” (Part 1 of 2): Long before COVID’s arrival, antibiotic-resistance was a quiet global pandemic. Now that secondary bacterial infections are killing so many vulnerable patients in the COVID era, the pressure is growing for policy makers to finally address the antibiotics market failure. A cardiologist-turned-biotech entrepreneur explains why the superbugs always win. Hosted by Jim Greenwood. by I AM BIO
29 min listen
Vaccines are a Virtue: As biotech researchers work around the clock on a covid vaccine, ill-informed, anti-science anti-vaxxers must be denounced and excoriated in the public square. BIO’s head of infectious disease policy Phyllis Arthur administers a vital dose of vaccine education, because none of us is safe until we all are. Hosted by Jim Greenwood. by I AM BIO
33 min listen
Bullish: Biotechnology investors, armed with troves of data and “misfit” minds, have become key-decision makers in everything from when to open up the states to which medicines can turn the tide in this pandemic the quickest. As the BIO Investor Forum kicks off virtually today, a biomedical renaissance has Wall Street bullish on biotech’s future. by I AM BIO
30 min listen
Destroying COVID's Genome: Alnylam Pharmaceuticals, which take its name from the center and brightest star in Orion’s Belt, is working on an RNAi therapy to destroy the genome of the novel coronavirus — and with it, its ability to replicate and kill. Hosted by Jim Greenwood. by I AM BIO
39 min listen
An Alternative to Flying Dirty (Redux): While Swedish climate activist Greta Thunberg has kindled a global dialogue about the ravages of climate change and the role of airline emissions, a Colorado biotech is putting forward a jaw-dropping alternative to flight shaming: actual jet fuel with no carbon footprint. Hosted by Jim Greenwood. by I AM BIO
40 min listen
Bats Don’t Have Passports: Modernity is plowing new frontiers, bringing us closer to exotic wildlife rich in viruses that our immune systems have not evolved to fight. Preventing future pandemics will require global cooperation, local action and a comprehensive strategy to monitor infectious disease hotspots to reduce the risk of zoonotic disease. Hosted by Jim Greenwood. by I AM BIO
33 min listen
Clinical Trials and Tribulations: As Moderna breaks the record for speed in starting the final stage of human testing for its covid vaccine, new BIO CEO Dr. Michelle McMurry-Heath tackles the thorny issue of how to best structure the historic Phase 3 clinical trial. The Boston biotech’s Chief Medical Officer reveals the strategy to test vaccine efficacy on communities of color and others hardest hit by the coronavirus. Hosted by Dr. Michelle McMurry-Heath by I AM BIO
29 min listen
The Greening of Medicine: As the pandemic lays bare the links between human and environmental health, neuroscience leader Biogen lays out the most aggressive fossil fuel elimination plan of any Fortune 500 company while doubling down on efforts to lead on clinical trial diversity and racial equity. by I AM BIO
30 min listen
COVID-19: We Were Warned: For years, leaders on the Bipartisan Commission on Biodefense told Congress and the White House that it wasn’t a matter of if, but when, a pandemic would happen. Exploring the panel’s unheeded recommendations can give the United States a blueprint for what to do going forward to protect us from the coronavirus and future threats. Hosted by Jim Greenwood. by I AM BIO
50 min listen
“Herd” Immunity (Redux): Biotech companies are working feverishly to develop antibody therapies to provide short-term protection against COVID-19. But what if the novel coronavirus mutates and outwits traditional monoclonal antibodies? Well, that’s where the super cows come in. Hosted by Jim Greenwood. by I AM BIO
36 min listen
The Antibody Test Shortage: Only antibody testing can tell us who has been infected and recovered from coronavirus and when it might be safe to return to work. There’s a massive global shortage of these tests, and a Maryland biotech is racing to bolster the U.S. supply. Hosted by Jim Greenwood. by I AM BIO
27 min listen
COVID-19’s True Origins (Redux): There's a joke among ecological health scientists that if “you don’t believe one person can change the world, try eating an undercooked bat.” However, what EcoHealth Alliance’s Dr. William Karesh — a world-renowned expert on zoonotic disease transmission — reveals about the trend line for animal-to-human viral transmission is no laughing matter. Hosted by Jim Greenwood. by I AM BIO
39 min listen

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Listener takeover: Your Biotech Questions Answered: YOU asked, and we answered. In this episode, we had our experts on standby to answer questions from you, our listeners. We discuss topics ranging from the safety of genetically modified foods (GMOs), to the new era of personalized medicine, feeding the world by 2050, and even what makes start-up companies attractive to investors. by I AM BIO
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Editing Cells Within the Body—a New CRISPR Frontier: With its potential to expand the horizons of what’s possible for patients, CRISPR is the new darling of biotech. Reaching an important milestone in 2023 with the FDA approval of a sickle cell treatment using CRISPR, the technology is poised to break new barriers for treating patients in the near future. In this episode we talk with two companies working together on the next generation of CRISPR: editing cells within the body. We discuss the progress and the challenge in making this breakthrough a reality. by I AM BIO
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Biotech is Climate Tech: Biotech companies are addressing climate change through innovation—from carbon neutral facilities to agricultural innovations to reduce greenhouse gas emissions. BIO was on the ground at the COP28 UN Climate Change Conference in Dubai to deliver the message that biotech is climate tech. by I AM BIO
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What We Know About the Microbiome: The gut microbiome, which consists of trillions of bacteria, viruses, and fungi, plays a crucial role in our health. However, there is still much to learn about this complex ecosystem. On this episode we talk with experts who tell us where the science is—how much we know, and how much we don’t. Two companies, Bloom Science and Seres Therapeutics, are leveraging the microbiome to develop new therapeutics. The potential of the microbiome is vast, and further research and technological advancements will continue to unlock its benefits. by I AM BIO
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Is CRISPR the New Sickle Cell Savior?: 2023 ended with an exciting biotech breakthrough for sickle cell patients. A gene-editing therapy using the revolutionary CRISPR technology provides new hope and options for the nearly 100,000 Americans with sickle cell disease. In this episode, we talk with the company behind one of the life-changing therapies, CASGEVY, and speak with two advocates for sickle cell patients. by I AM BIO
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28 min listen
The Synbio Revolution is Here: Innovative companies are using synthetic biology to engineer organisms and create new materials that could transform every sector of our economy, from health care to food and energy production. Those companies say we’ve entered a synbio revolution, and it holds potential to improve the health of people and our planet. In this episode, we talk with three synbio experts about how this convergence of genetic engineering, computer science and other scientific disciplines is making our world more sustainable. by I AM BIO
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25 min listen
We Need Bees. Bees Need Biotech.: Bees and other pollinators are critical to our survival, with one out of every three bites of food we eat depending on pollination to produce. That’s why reports of a decline in bee populations and rising threats from pests, viruses and environmental pressures, including climate change, are alarming. In this episode we talk with an expert on bees and other pollinators about how bees are doing and why it’s important to save them. We also talk with two biotech leaders whose companies are working to improve bee health through development of innovative treatments for some of the worst threats faced by bees. by I AM BIO
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Sickle Cell Saviors

Sickle Cell Saviors

Description

Titles in the series (100)

More Episodes from I AM BIO