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60. Part 2: How not to die of chronic disease or COVID (aka how to avoid insulin resistance), with Tommy Wood, MD/PhD

60. Part 2: How not to die of chronic disease or COVID (aka how to avoid insulin resistance), with Tommy Wood, MD/PhD

FromPaul Saladino MD podcast


60. Part 2: How not to die of chronic disease or COVID (aka how to avoid insulin resistance), with Tommy Wood, MD/PhD

FromPaul Saladino MD podcast

ratings:
Length:
160 minutes
Released:
Jul 27, 2020
Format:
Podcast episode

Description

The second edition of The Carnivore Code (new cover and index!) is available for pre-order now!  www.Thecarnivorecodebook.com release date is August 4th 2020 in ebook, print, and audiobook formats.    Tommy Wood MD, PhD is an elite-level professional nerd who has coached world class athletes in a dozen sports.  He has an undergraduate degree in biochemistry from the University of Cambridge, a medical degree from the University of Oxford, and a PhD in physiology and neuroscience from the University of Oslo. Tommy is a Research Assistant Professor at the University of Washington, a Research Scientist at the Institute for Human and Machine cognition, and is on the scientific advisory board of Hintsa Performance. He is also CSO (Chief Snake Officer) at the Costa Rican Center for Bro Research. Tommy lives in Seattle with his wife Elizabeth and their two goofy boxers. In his spare time he can usually be found cooking, reading, or lifting something heavy.   Time Stamps:   10:15 Tommy on Coronavirus. 13:00 Why it's okay to be wrong as a scientist. 15:00 Where are we now with Coronavirus? (12:24) (14:20-14:59)   22:17 Boris Johnson Moves To Ban Junk Food Discount Deals To Fight Obesity https://www.independent.co.uk/news/uk/politics/boris-johnson-junk-food-ban-buy-one-get-one-free-obesity-coronavirus-a9611766.html   24:45. Tommy’s article on metabolic health and pandemics.Metabolic health and lifestyle medicine should be a cornerstone of future pandemic preparedness Metabolic health and lifestyle medicine should be a cornerstone of future pandemic preparedness https://onlinelibrary.wiley.com/doi/full/10.1002/lim2.2   27:45  COVID-19 severity is predicted by earlier evidence of accelerated aging https://www.medrxiv.org/content/10.1101/2020.07.10.20147777v1   37:10 Is there an ideologically ‘’perfect’’ diet.   40:25 How does metabolic health affect our immune system? (38:44)   FIGURE 41:47  An elastic-net logistic regression approach to generate classifiers and gene signatures for types of immune cells and T helper cell subsets https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-019-2994-z   42:55 The NLRP3 inflammasome: Role in metabolic disorders and regulation by metabolic pathways https://pubmed.ncbi.nlm.nih.gov/29339210/ 45:15   Analysis and modulation of the TH1/TH2 cytokine balance https://www.imd-berlin.de/en/subject-information/diagnostics-information/th1th2-cytokine-balance.html   46:57  Relationship between neutrophil-lymphocyte ratio and insulin resistance in newly diagnosed type 2 diabetes mellitus patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357061/   56:10. Are ethnic populations at greater risk?     59:10  Impact of obesity and metabolic syndrome on immunity https://academic.oup.com/advances/article/7/1/66/4524061   60:15. Insulin Resistance.    1:14:50 What causes pathologic insulin resistance?   1:19:07 Polyunsaturated fatty acids (1:19:30)    1:19:29  Increase of Adipose tissue little lake acid in US adults in the last half centuryhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4642429/   1:32:29   Tissue levels of polyunsaturated fatty acids during early human development https://pubmed.ncbi.nlm.nih.gov/1532827/   1:31:52  Differential metabolic effects of saturated versus polyunsaturated fats in ketogenic dietshttps://pubmed.ncbi.nlm.nih.gov/15070924/   1:35:52   Dietary a little lake acid elevates endogenous 2-AG anandamide and induces obesity https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/   1:37:10 Saturated fatty acids (studies) (1:50:20)   1:37:33  Effects of step-wise increase in dietary carbohydrate on circulating saturated fatty acids and palmitoleic acid in adults with metabolic syndrome https://pubmed.ncbi.nlm.nih.gov/25415333/   1:46:14. Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice https://pubmed.ncbi.nlm.nih.gov/25222131/   1:47:53 Elevated serum C-reactive protein and free fatty acids among non-diabetic carriers of missense
Released:
Jul 27, 2020
Format:
Podcast episode

Titles in the series (100)

Throughout my training and practice as a physician I have come to one very disappointing conclusion: Western medicine isn’t helping people lead better lives. Now that I’ve realized this, I’ve become obsessed with understanding what makes us healthy or ill. I want to live the best life I can and I want to be able to share this knowledge with others so that they can do the same. This podcast is the result of my relentless search to understand the roots of chronic disease. If you want to know how to live the most radical life possible I hope you’ll join me on this journey.