Your DNA alone is worthless. So claim my guests on today's show, Dr. Matt Dawson and Dr. Mike Mallin of , with locations in Versailles, KY, and Bend, OR. I first interviewed these guys in the episode "" and now they're back to talk all things DNA and genetics. Dr. Matt Dawson is a precision medicine physician in Lexington, KY, co-host of the and has been obsessed with performance optimization as long as he can remember. He received scholarships to play two sports in college even with “minimal talent” because of his voracious reading and implementation of any fitness or nutritional techniques that would give him an edge. Dr. Dawson continued that obsession in medical school and, as a physician, he has won national awards for education, innovation, and leadership. He has lectured in over 20 countries and trained thousands of other physicians through live lecture, online education, two textbooks, and an educational app. Dr. Dawson combines his training in genomics and functional medicine to give personalized, precise medical guidance. His obsession with performance optimization has morphed from initially athletic to now mental performance and longevity. Whether it's a professional athlete or a grandparent optimizing their mental clarity and mobility to keep up with their grandkids, Dr. Dawson is passionate about helping everyone perform at their absolute peak. Dr. Mike Mallin is a physician in Bend, OR who is obsessed with health performance and precision medicine and is co-founder of the . He completed medical school in South Carolina and trained in Emergency Medicine in Salt Lake City, UT where he competed in several ultramarathons and found his love for the mountains and performance. Mike currently practices in Bend, OR and Lexington, KY in his precision medicine clinics. He is also co-founder of the , an educational podcast that has taught thousands of physicians all over the world how to use ultrasound, as well as , his podcast focusing on health performance and longevity. During our discussion, you'll discover: -Why DNA data in and of itself is insufficient... Epigenomics: Genomics taken in context of the whole person Get a sense of what a person's genes are transcribing via lab values Understand how lifestyle and habits can affect specific genes (ex. PGC1A) Needed a simplified means of interpreting genetic results Falsehoods have been noted in DNA reports A comprehensive analysis includes lifestyle, preferences, microbiome, etc. DNA reports will occasionally translate RSID's wrong Misreading data can lead to unhealthy lifestyle decisions -What sets Drs. Dawson and Mallin's new software apart from other DNA software... Lifestyle and patient preferences factor heavily Microbiome data is important Looking for a more comprehensive picture of a patient than simple data Cholesterol levels, cardiovascular conditions, etc. are taken into account -The results from the software thus far... "Whole picture" approach allows for more accurate diagnoses and appropriate recommendations Cardiovascular risk down  by over 50% in less than 6 months on average LP(a) decreases more than 2 years of statin treatment LDL-P down an average of 357 points per patient CRP down over 50% in patients who start off with it elevated Average HRV increase of 15 from genomic based training programs All mostly without pharmaceuticals -How Matt and Mike test for aging, and their "gold standard" longevity protocol... Get the basics right first: sleep, environment, exercise, sunlight, etc. Personalized: genomics, preference based Get biological age first: True Age Test DNA Age Test Horvath Clock tests methylation in the body; telomere test results have been erratic Pulse press cycle is important MOTS-C Article: Use peptides w/ caution; opt for natural treatments first Exercise protocols used during anabolic phase of treatment and endurance Short interval Longevity exercise programs Fasting, , Dr. John Douillard's Dr. Valter Longo's -NAD prot