The Fellowship of the TWiM reveal that colorectal cancer-associated microbiota are associated with higher numbers of methylated genes in colonic mucosa, and identification of metabolites needed by the fire blight disease bacterium for virulence in apples. Become a patron of TWiM. Links for this episode: Colorectal cancer and the gut microbiome (PNAS) Fire blight (YouTube) Fire blight spreads north (NY Times) E. amylovora auxotrophs (Appl Environ Micro) Music used on TWiM is composed and performed by Ronald Jenkees and used with permission. Send your microbiology questions and comments to twim@microbe.tv