TWiM #3: Anthrax, genomics and the FBI inquiry

FromThis Week in Microbiology

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TWiM #3: Anthrax, genomics and the FBI inquiry

FromThis Week in Microbiology

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Length:

60 minutes

Released:

Mar 23, 2011

Format:

Podcast episode

Description

Vincent, Jo, Cliff, and Ron explore the genome analysis done in support of the Amerithrax investigation, and an insecticidal enterotoxin-deficient mutant of Bacillus thurigiensis.

Released:

Mar 23, 2011

Format:

Podcast episode

Titles in the series (100)

This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.

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TWiM #21: Symbiotic margheritas: Vincent and Elio discuss ancient symbiosis between Alphaproteobacteria and catenulid flatworms, and a toxin from Helicobacter pylori that engages the mitochondrial fission machinery to induce host cell death. by This Week in Microbiology
68 min listen
TWiM #11: Chickens, antibiotics, and asthma: Vincent, Margaret, Michael and Elio review the presence of extended spectrum beta-lactamase genes in chicken meat and in humans, and a beneficial effect of Helicobacter pylori colonization on the development of allergen-induced asthma. by This Week in Microbiology
73 min listen
TWiM #6: Antibacterial therapy with bacteriophage: Reality or fiction?: Vincent, Cliff, Michael and Elio review the use of bacteriophages to manage infections, and the presence of antibiotic resistance genes in the bacteriophage from urban sewage and river water. by This Week in Microbiology
82 min listen
TWiM #1: Neisseria LINEs up: On episode #1 of the podcast This Week in Microbiology, Vincent, Cliff, Michael, and Stan discuss transfer of DNA from a human host to a bacterial pathogen, and the ability of dry copper to kill bacteria on contact. by This Week in Microbiology
63 min listen
TWiM # 8: Live in NOLA: Vincent, Michael, and Stanley recorded TWiM #8 live at the 2011 ASM General Meeting in New Orleans, with guests Andreas Baümler, Nicole Dubilier, and Paul Rainey. They spoke about how pathogens benefit from disease, symbioses between... by This Week in Microbiology
86 min listen
TWiM #9: Bean sprouts and E. coli O104:H4: Vincent, Michael, and Cliff review the outbreak of bloody diarrhea and hemolytic uremic syndrome in Germany caused by Shiga toxin-producing Escherichia coli O104:H4. by This Week in Microbiology
77 min listen
TWiM #25: Magnetotactic bacteria and totally drug resistant TB: On episode #25 of the podcast, Vincent, Elio, and Michael review bacteria that use the earth’s magnetic field for navigation, and identification of totally drug resistant Mycobacterium tuberculosis. by This Week in Microbiology
77 min listen
TWiM #23: Fighting antibiotics with toxic gas and starvation: Vincent, Jo, Elio, and Michael explain how a swarming bacterium helps disperse a non-motile fungus, and bacterial antibiotic tolerance mediated by hydrogen sulfide and starvation responses. by This Week in Microbiology
76 min listen
TWiM #5: Mercury-methylating Desulfovibrio and antimicrobial nanoparticles: Vincent, Ron, Cliff, and Michael discuss the genome sequence of a mercury-methylating bacterium and the antimicrobial effects of nanoparticles. by This Week in Microbiology
76 min listen
TWiM #10: A symbiotic cloaking device: On episode #10 of the podcast This Week in Microbiology, Vincent, Margaret, Elio, Michael and Dickson discuss the symbiosis between the Hawaiian bobtail squid and the luminous, gram-negative bacterium Vibrio fischeri. by This Week in Microbiology
68 min listen
TWiM #17: Debugging endosymbiosis: Vincent, Michael, and Elio focus on endosymbiosis: the rapid spread of Ricekttsia in whitefiles, and a metabolic patchwork in nested symbionts of mealybugs. by This Week in Microbiology
71 min listen
TWiM #7: Cycles of life and death, light and dark: Vincent, Cliff, Elio, Margaret, and Michael discuss programmed cell death in E. coli, and the daily synthesis and degradation of enzymes needed for photosynthesis and nitrogen fixation by cyanobacteria. by This Week in Microbiology
64 min listen
TWiM #19: Your microbiome is what you eat: Vincent, Michael, Elio, and Jo discuss the genome sequence of Y. pestis from victims of the Black Death, and the effect of diet on gut microbial enterotypes. by This Week in Microbiology
59 min listen
TWiM #2: The plague, microbial virulence and the gut microbiome: Vincent, Cliff, and Michael review a fatal laboratory acquired Yersinia pestis infection, and how gut bacteria control body weight and metabolic activity. by This Week in Microbiology
76 min listen
TWiM #12: Photothermal nanoblades and genome engineering: Vincent, Margaret, Michael and Elio review the use of photothermal nanoblades to dissect the Burkholderia intracellular life cycle, and manipulation of chromosomes in vivo for genome-wide codon replacement in E. coli. by This Week in Microbiology
75 min listen
TWiM #20: Facebook for bacteria: On episode #20 of the podcast This Week in Microbiology, Vincent, Michael, and Elio follow up on the outbreaks of E. coli in Germany and cholera in Haiti, then discuss genes that confer self-identity to Proteus mirabilis. by This Week in Microbiology
68 min listen
TWiM #44: Phage interruptus: Vincent, Michael, Elio discuss the role of prophage excision in exit of Listeria from the phagosome, and analysis of bacterial communities in saliva. by This Week in Microbiology
66 min listen
TWiM #14: Vomocytosis and microbial transistors: On episode #14 of the podcast This Week in Microbiology, Stanley, Margaret, Michael and Elio review how the fungus Cryptococcus escapes from macrophages, and electrical conductivity in nanowires formed by the bacterium Geobacter. by This Week in Microbiology
68 min listen
TWiM #13: Probiotics and inflammasomes: Telling good bacteria from the bad: On episode #13 of the podcast This Week in Microbiology, Stanley, Jo, Michael and Elio discuss how colonic microbial ecology and risk for colitis are regulated by an inflammasome, and amelioration of intestinal inflammation in mice by delivery of... by This Week in Microbiology
58 min listen
TWiM #16: ICAAC Live: On episode #16 of the podcast This Week in Microbiology, Vincent, Michael, Arturo, Stuart, and David converse about antimicrobial resistance and why most fungi do not cause disease at the 51st Interscience Conference... by This Week in Microbiology
89 min listen
TWiM #4: Cantaloupes and Salmonella gastroenteritis: Vincent, Cliff, Margaret, and Michael review foodborne bacterial illness in the context of outbreaks associated with cantaloupes and Lebanon bologna. by This Week in Microbiology
75 min listen
TWiM #34: Doing the DISCO with Emiliania: Hosts: Vincent Racaniello, Michael Schmidt, and Elio Schaechter Vincent, Michael, and Elio discuss changing populations of Emiliania huxleyi and their viruses in the North and Black Seas. Right click to download TWiM... by This Week in Microbiology
69 min listen
TWiM #15: Microbial long distance relationships: On episode #15 of the podcast This Week in Microbiology, Vincent, Michael and Jo review the number of species on Earth, evidence that the 2010 Haitian cholera outbreak originated in Nepal, and how gut microbiota influence the immune response to... by This Week in Microbiology
59 min listen
TWiM #30: Unraveling melioidosis and insulin resistance: On episode #30 of the podcast, Vincent, Elio, and Michael review how a toxin from Burkholderia pseudomallei inhibits protein synthesis, and the role of the gut microbiome in modulating insulin resistance in mice lacking an innate immune sensor. by This Week in Microbiology
70 min listen
TWiM #47: Resistance on the surface: Horizontal transfer of antibiotic resistance genes on metal surfaces, and using bacteriophage to reverse antibiotic resistance. by This Week in Microbiology
71 min listen
TWiM 31: Screen door on a submarine: Hosts: Vincent Racaniello, Jo Handelsman, and Michael Schmidt Vincent, Jo, and Michael discuss an archetypal protein transport system in bacterial outer membranes, and evidence that gut microbial enterotypes might not fall into... by This Week in Microbiology
75 min listen
TWiM #3: Anthrax, genomics and the FBI inquiry: Vincent, Jo, Cliff, and Ron explore the genome analysis done in support of the Amerithrax investigation, and an insecticidal enterotoxin-deficient mutant of Bacillus thurigiensis. by This Week in Microbiology
60 min listen
TWiM #22: Microbiology 911: Vincent and Michael speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about microbial infections encountered in the emergency room. by This Week in Microbiology
98 min listen
TWiM #18: Escherichia coli K-12, an emerging pathogen?: Vincent, Michael, Elio, and Stanley explain how to make the human intestinal commensal and benign laboratory bacterium Escherichia coli K-12 into an invasive organism, and the unearthing of century-old spores in New York City. by This Week in Microbiology
74 min listen
TWiM #27: An inflamed gut is good for Salmonella: Vincent, Elio, and Michael review how inflammation allows Salmonella to compete with fermenting gut microbes, and a riboswitch in bacterial and Archeal species that is triggered by fluoride. by This Week in Microbiology
75 min listen

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309: Stomach Acid Can Be Your Friend: Today on TWiM, a charcuterie invasion, and how that acid in your stomach may protect from the invading hordes of microbes. Hosts: , and . Become a of TWiM. Links for this episode Commentary: Peeling the onion: Send your microbiology... by This Week in Microbiology
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308: Living in a Community World: TWiM reviews a case of E. faecium bacteremia treated with combination bacteriophage and antibiotic therapy, and how dopamine receptor D2 confers colonization resistance via microbial metabolites. Hosts: , , and . Guest: Become a of TWiM. Links for... by This Week in Microbiology
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305: The Marvel of MAC: TWiM reviews the ongoing cholera outbreak in Africa, and research showing that gut complement induced by the microbiota blocks pathogens and spares commensal bacteria. Hosts: , , and . Become a of TWiM. Links for this episode (Africa CDC) Deadly ... by This Week in Microbiology
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303: Can Our Microbiome Break Our Hearts?: TWiM reveals a database of genome sequences of thousands of Mycobaterium tuberculosis, allowing association with resistance phenotypes to 13 antibiotics, and microbe-derived uremic solutes that enhance thrombosis potential in the host. Hosts: , , and... by This Week in Microbiology
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302: Itching and Scratching and New Antibiotics: TWiM describes the mechanism for the S. aureus itch and scratch induced skin damage, and discovery of a novel class of antibiotics that targets the lipopolysaccharide transporter. Become a of TWiM. Links: S. aureus drives... by This Week in Microbiology
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301: Another Year is Microbial: A highly reduced TWiM team presents a study of the use of phage diversity in cell-free DNA to identify bacterial pathogens in human sepsis cases, and the evolution, persistence, and host adaptation of a gonococcal antimicrobial resistance plasmid that... by This Week in Microbiology
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300: Marvels of Microbiology: On the occasion of TWiM’s 300th episode, we discuss how two college students found a new antibiotic in soil, Barbara Iglewski’s passing, and Elio returns for an appearance. Hosts: , , and . Guest: Become a of TWiM. Links for this episode ... by This Week in Microbiology
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299: Teaching with TWiM: From ASM’s Conference for Undergraduate Educators 2023 in Phoenix, TWiM speaks with Amaya Garcia Costas and Gwendolyn Knapp about their approaches to undergraduate microbiology education, and how they use TWiM as part of their curricula. Hosts: , , ... by This Week in Microbiology
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298: Impact of Lung Microbiome and Racial Disparities on Asthma: TWiM provides thoughts on providing better training for a non-academic career, and help celebrate Black in Microbiology Week with a 2023 paper by Ari Kozik, a co-founder of and Assistant Professor at the University of Michigan Hosts: , , , , Become a... by This Week in Microbiology
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297: Bacterial-electronic Sensor Pill: TWiM reviews how a coating of lipoproteins provides a stabilizing environment on the inner membrane of Bacillus subtilis spores, and a miniaturized device that integrates genetically engineered probiotic biosensors with a custom-designed photodetector... by This Week in Microbiology
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296: Bacterial Channels in Plant Cells: TWiM discusses a dispute about whether the mycobiome plays a role in the development of cancer, and the structure and function of channels that are delivered to plant cells by pathogenic bacteria. Hosts: , and . Become a of TWiM. Links for this... by This Week in Microbiology
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295: Uncultured and Unmutable: TWiM explains how phages avoid tRNA-targeting host defenses, and discovery of a new antibiotic from an uncultured bacterium that binds to an immutable target. Hosts: , , and , Become a of TWiM. Links for this episode host defenses (eLife) New... by This Week in Microbiology
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294: You’ll Scream After Ice Cream: TWiM reveals that the ice cream manufacturing environment harbors psychrotrophic bacteria, and identification of a deadly bacterial strain causing widespread deaths of newborns in Uganda. Hosts: , , & . Become a of TWiM. Links for this episode ... by This Week in Microbiology
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291: Biogeography of Tectonics and Teeth: TWiM explains how photoferrotrophic bacteria initiated plate tectonics over 2500 million years ago, and how two bacteria work together to cause childhood tooth decay. Hosts: , , , , Guest: Subscribe to TWiM (free) on , , , , or by Become a of... by This Week in Microbiology
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290: Houston, We Have Mimi Goldschmidt: From ASM Microbe 2023 in Houston, TWiM speaks with Mimi Goldschmidt about her remarkable career in microbiology which included training astronauts to safely bring moon rocks back to Earth. Hosts: , , . Guest: Become a of TWiM. Links for this... by This Week in Microbiology
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288: Cancer and E. coli: TWiM describes a potential connection between a bacterial protein that damages DNA, and human cancers, and how to synthesize antimicrobial natural products from reconstructed bacterial genomes of the Middle and Upper Paleolithic. Hosts: , , , . Become... by This Week in Microbiology
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287: When Replicas Do Not Replicate: TWiM investigates the high variability in the rate and amount of current production from microbial fuel cells, and how bacteria link their growth rate to external nutrient conditions via a protein that functions as a cellular rheostat. Hosts: , , . ... by This Week in Microbiology
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286: When Replicas Do Not Replicate by This Week in Microbiology
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285: How Plague Got Deadly: TWiM reveals a new type of satellite virus that requires only phage tails for producing infectious virus particles, and that highly virulent plague bacteria differs from its innocuous enteric predecessor by its resistance to lysis by human complement.... by This Week in Microbiology
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284: Flies, Pigs, and Squid: TWiM reveals housefly dispersal of antimicrobial resistant bacteria, and a reproductive organ in squid linked to symbiotic bacteria. Links for this episode (Appl Micro Int) (Nature) (PLoS Glob Pub Health) (mBio) y! by This Week in Microbiology
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283: Quorum Sensing In The Gut: TWiM reveals quorum-sensing systems that regulate intestinal inflammation and permeability caused by P. aeruginosa, and how plasmids manipulate bacterial behavior through translational regulatory crosstalk. Hosts: , , , . Become a of TWiM. Links for... by This Week in Microbiology
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282: At-home Evolution With Yeast: TWiM presents a protocol for evolving caffeine-tolerant yeast by high school students in the home, and how predator-prey dynamics change when multiple bacteria grow together in biofilms. Hosts: , , , . Guest: Subscribe to TWiM (free) on , , , , or... by This Week in Microbiology
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280: Magnesium Modulates by This Week in Microbiology
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TWiM #3: Anthrax, genomics and the FBI inquiry

TWiM #3: Anthrax, genomics and the FBI inquiry

Description

Titles in the series (100)

More Episodes from This Week in Microbiology

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