This powerhouse writer (the first black woman ever to win a comedy writing Emmy), actress ('Master of None' and 'Ready Player One') and creator/producer (Showtime's new series about Chicago's South Side) — who recently appeared on Vanity Fair's cover and was named by Time as one of the world's 100 most influential people — reflects on her upbringing, the importance of mentorship and the kaleidoscopic way her career has come together.

But first: Natalie Jarvey, THR's digital media editor, joins Scott to discuss her cover story chronicling the rise of — and challenges facing — Hulu, the streaming service behind 'The Handmaid's Tale.'