The dashing Oscar nominee looks back on 25 years in the biz, from kid parts ('City Slickers') to teen roles ('Donnie Darko') to his first grown-up characters ('Brokeback Mountain'); lessons learned from the flop of 'Prince of Persia: The Sands of Time'; and how recalibrating his approach led to a streak of great performances ('Source Code,' 'End of Watch,' 'Prisoners,' 'Nightcrawler,' 'Southpaw,' 'Nocturnal Animals' and 'Stronger').

But first: Lynne Segall, EVP and group publisher of The Hollywood Reporter and Billboard, joins Scott to discuss THR's history and brand, how awards season impacts ad sales and what it was like following Tichi Wilkerson and Katharine Graham into publishing when few other women were in positions of power in media.