Get our free clinical lab guide: https://www.medgeek.co/clinical-lab-guide25 - Today, we have a 35 year old African American female with a past medical history of hypertension, who presents to the emergency department. He has a two week history of a viral upper respiratory symptoms, including a low grade fever, cough, nasal congestion, rhinorrhea, sore throat, decreased oral intake - followed by a persistent nose bleed. The nose bleed began over the last couple days and isn't stopping despite persistent pressure. And over the last 24 hours, she had a change in her mental status per her family. Her exam was unremarkable. Her vitals: 100.2 F, HR 90s, BP 145/82, and 98% O2 RA.  Initial labs revealed: WBC: 18,000 H/H: 9/27 Platelets: 7,000 Creatinine: 1.4 Total bilirubin: 3 LDH: 1,500 Normal fibrinogen, D-dimer, PT, INR Peripheral smear: moderate schistocytes What's your diagnosis? Well, at this point, we are thinking Thrombotic thrombocytopenic purpura (TTP). Today, we are going to break this disease down for you. - Follow us on Instagram here: https://www.instagram.com/medgeeksinc - Check out our course material here: https://learn.medgeeks.co - This podcast should not be used in any legal capacity whatsoever, including but not limited to establishing standard of care in a legal sense or as a basis for expert witness testimony. No guarantee is given regarding the accuracy of any statements or opinions made on the podcast, video, or blog.