This audio program includes a case of folie à deux and infanticide, the DSM-5 changes in sleep disorder classification, and new research on ketamine for treatment-resistant depression. Two reports explore brain structure and functioning in patients with eating disorders. Additional studies examine neural mechanisms of frustration in chronically irritable children and the role of oxytocin in mental illness and its treatment. One study looked at the effect of oxytocin on social threat hypersensitivity in women with borderline personality disorder. Another one analyzed how oxytocin moderates the relationship between maternal depression and child mental health. Articles can be viewed online at www.ajp.psychiatryonline.org.