Lab On A Chip: Low-cost point-of-care devices for human diseases diagnosis, possibly making laboratories dispensable

By Fouad Sabry

What Is Lab on a Chip

A lab-on-a-chip (LOC) is a device that integrates one or several laboratory functions on a single integrated circuit of only millimeters to a few square centimeters to achieve automation and high-throughput screening. LOCs can handle extremely small fluid volumes down to less than pico-liters. Lab-on-a-chip devices are a subset of microelectromechanical systems (MEMS) devices and sometimes called "micro total analysis systems" (mTAS). LOCs may use microfluidics, the physics, manipulation and study of minute amounts of fluids. However, strictly regarded "lab-on-a-chip" indicates generally the scaling of single or multiple lab processes down to chip-format, whereas "mTAS" is dedicated to the integration of the total sequence of lab processes to perform chemical analysis. The term "lab-on-a-chip" was introduced when it turned out that mTAS technologies were applicable for more than only analysis purposes.

How You Will Benefit

(I) Insights, and validations about the following topics:

Chapter 1: Lab-on-a-chip

Chapter 2: Assay

Chapter 3: Dielectrophoresis

Chapter 4: Immunoassay

Chapter 5: Electrophysiology

Chapter 6: Microfluidics

Chapter 7: Materials science

(II) Answering the public top questions about lab on a chip.

(III) Real world examples for the usage of lab on a chip in many fields.

(IV) 17 appendices to explain, briefly, 266 emerging technologies in each industry to have 360-degree full understanding of lab on a chip' technologies.

Who This Book Is For

Professionals, undergraduate and graduate students, enthusiasts, hobbyists, and those who want to go beyond basic knowledge or information for any kind of lab on a chip.

• Language: English
• Publisher: One Billion Knowledgeable
• Release date: Jan 16, 2022

Book preview

Lab on a Chip

Other Books by The Author

1 - Plasma Propulsion

2 - Pulse Detonation Engine

3 - Agricultural Robotics

4 - Closed Ecological Systems

5 - Cultured Meat

6 - Vertical Farming

7 - Autonomous Vehicles

8 - Autonomous Drones

9 - Autonomous Robotics

10 - Autonomous Weapons

11 - Arcology

12 - 4D Printing

13 - Domed City

14 - Distributed Ledger

15 - Digital Currency

16 - Decentralized Finance

17 - Smart Machines

18 - Aerogel

19 - Amorphous Metal

20 - Bioplastic

21 - Conductive Polymer

22 - Cryogenic Treatment

23 - Dynamic Armour

24 - Fullerene

25 - Graphene

26 - Lab on a Chip

27 - High Temperature Superconductivity

28 - Magnetic Nanoparticles

29 - Magnetorheological Fluid

30 - Microfluidics

31 - Superfluidity

32 - Metamaterial

33 - Metal Foam

34 - Multi Function Structure

35 - Nanomaterials

36 - Programmable Matter

37 - Quantum Dot

38 - Silicene

39 - Superalloy

40 - Synthetic Diamond

41 - Time Crystal

42 - Translucent Concrete

43 - Brain Computer Interface

44 - Swarm Intelligence

Series by The Author

Emerging Technologies in Aerospace

1 - Plasma Propulsion

2 - Pulse Detonation Engine

Emerging Technologies in Agriculture

1 - Agricultural Robotics

2 - Closed Ecological Systems

3 - Cultured Meat

4 - Vertical Farming

Emerging Technologies in Autonomous Things

1 - Autonomous Vehicles

2 - Autonomous Drones

3 - Autonomous Robotics

4 - Autonomous Weapons

Emerging Technologies in Construction

1 - Arcology

2 - 4D Printing

3 - Domed City

Emerging Technologies in Finance

1 - Distributed Ledger

2 - Digital Currency

3 - Decentralized Finance

Emerging Technologies in Information Technology

1 - Smart Machines

Emerging Technologies in Materials Science

1 - Aerogel

2 - Amorphous Metal

3 - Bioplastic

4 - Conductive Polymer

5 - Cryogenic Treatment

6 - Dynamic Armour

7 - Fullerene

8 - Graphene

9 - Lab on a Chip

10 - High Temperature Superconductivity

11 - Magnetic Nanoparticles

12 - Magnetorheological Fluid

13 - Microfluidics

14 - Superfluidity

15 - Metamaterial

16 - Metal Foam

17 - Multi Function Structure

18 - Nanomaterials

19 - Programmable Matter

20 - Quantum Dot

21 - Silicene

22 - Superalloy

23 - Synthetic Diamond

24 - Time Crystal

25 - Translucent Concrete

Emerging Technologies in Neuroscience

1 - Brain Computer Interface

Emerging Technologies in Robotics

1 - Swarm Intelligence

One Billion Knowledgeable

Lab on a Chip

Low-cost point-of-care devices for human diseases diagnosis, possibly making laboratories dispensable

Fouad Sabry

Copyright

Lab on a Chip Copyright © 2021 by Fouad Sabry. All Rights Reserved.

All rights reserved. No part of this book may be reproduced in any form or by any electronic or mechanical means including information storage and retrieval systems, without permission in writing from the author. The only exception is by a reviewer, who may quote short excerpts in a review.

Cover designed by Fouad Sabry.

This book is a work of fiction. Names, characters, places, and incidents either are products of the author’s imagination or are used fictitiously. Any resemblance to actual persons, living or dead, events, or locales is entirely coincidental.

Bonus

You can send an email to [e-mail] with the subject line Lab on a Chip: Low-cost point-of-care devices for human diseases diagnosis, possibly making laboratories dispensable, and you will receive an email which contains the first few chapters of this book.

Fouad Sabry

Visit 1BK website at

www.1BKOfficial.org

Preface

Why did I write this book?

The story of writing this book started on 1989, when I was a student in the Secondary School of Advanced Students.

It is remarkably like the STEM (Science, Technology, Engineering, and Mathematics) Schools, which are now available in many advanced countries.

STEM is a curriculum based on the idea of educating students in four specific disciplines — science, technology, engineering, and mathematics — in an interdisciplinary and applied approach. This term is typically used to address an education policy or a curriculum choice in schools. It has implications for workforce development, national security concerns and immigration policy.

There was a weekly class in the library, where each student is free to choose any book and read for 1 hour. The objective of the class is to encourage the students to read subjects other than the educational curriculum.

In the library, while I was looking at the books on the shelves, I noticed huge books, total of 5,000 pages in 5 parts. The books name is The Encyclopedia of Technology, which describes everything around us, from absolute zero to semiconductors, almost every technology, at that time, was explained with colorful illustrations and simple words. I started to read the encyclopedia, and of course, I was not able to finish it in the 1-hour weekly class.

So, I convinced my father to buy the encyclopedia. My father bought all the technology tools for me in the beginning of my life, the first computer and the first technology encyclopedia, and both have a great impact on myself and my career.

I have finished the entire encyclopedia in the same summer vacation of this year, and then I started to see how the universe works and to how to apply that knowledge to everyday problems.

My passion to the technology started mor than 30 years ago and still the journey goes on.

This book is part of The Encyclopedia of Emerging Technologies which is my attempt to give the readers the same amazing experience I had when I was in high school, but instead of 20th century technologies, I am more interested in the 21st century emerging technologies, applications, and industry solutions.

The Encyclopedia of Emerging Technologies will consist of 365 books, each book will be focused on one single emerging technology. You can read the list of emerging technologies and their categorization by industry in the part of Coming Soon, at the end of the book.

365 books to give the readers the chance to increase their knowledge on one single emerging technology every day within the course of one year period.

Introduction

How did I write this book?

In every book of The Encyclopedia of Emerging Technologies, I am trying to get instant, raw search insights, direct from the minds of the people, trying to answer their questions about the emerging technology.

There are 3 billion Google searches every day, and 20% of those have never been seen before. They are like a direct line to the people thoughts.

Sometimes that’s ‘How do I remove paper jam’. Other times, it is the wrenching fears and secret hankerings they would only ever dare share with Google.

In my pursuit to discover an untapped goldmine of content ideas about Lab on a Chip, I use many tools to listen into autocomplete data from search engines like Google, then quickly cranks out every useful phrase and question, the people are asking around the keyword Lab on a Chip.

It is a goldmine of people insight, I can use to create fresh, ultra-useful content, products and services. The kind people, like you, really want.

People searches are the most important dataset ever collected on the human psyche. Therefore, this book is a live product, and constantly updated by more and more answers for new questions about Lab on a Chip, asked by people, just like you and me, wondering about this new emerging technology and would like to know more about it.

The approach for writing this book is to get a deeper level of understanding of how people search around Lab on a Chip, revealing questions and queries which I would not necessarily think off the top of my head, and answering these questions in super easy and digestible words, and to navigate the book around in a straightforward way.

So, when it comes to writing this book, I have ensured that it is as optimized and targeted as possible. This book purpose is helping the people to further understand and grow their knowledge about Lab on a Chip. I am trying to answer people’s questions as closely as possible and showing a lot more.

It is a fantastic, and beautiful way to explore questions and problems that the peoples have and answer them directly, and add insight, validation, and creativity to the content of the book – even pitches and proposals. The book uncovers rich, less crowded, and sometimes surprising areas of research demand I would not otherwise reach. There is no doubt that, it is expected to increase the knowledge of the potential readers’ minds, after reading the book using this approach.

I have applied a unique approach to make the content of this book always fresh. This approach depends on listening to the people minds, by using the search listening tools. This approach helped me to:

Meet the readers exactly where they are, so I can create relevant content that strikes a chord and drives more understanding to the topic.

Keep my finger firmly on the pulse, so I can get updates when people talk about this emerging technology in new ways, and monitor trends over time.

Uncover hidden treasures of questions need answers about the emerging technology to discover unexpected insights and hidden niches that boost the relevancy of the content and give it a winning edge.

Stop wasting time on gutfeel and guesswork about the content wanted by the readers and fill the book content with what the people need and say goodbye to the endless content ideas based on speculations.

Make solid decisions, and take fewer risks, to get front row seats to what people want to read and want to know — in real time — and use search data to make bold decisions, about which topics to include and which topics to exclude.

Streamline my content production to identify content ideas without manually having to sift through individual opinions to save days and even weeks of time.

It is wonderful to help the people to increase their knowledge in a straightforward way by just answering their questions.

I think the approach of writing of this book is unique as It collates, and tracks the important questions being asked by the readers on search engines.

Acknowledgments

Writing a book is harder than I thought and more rewarding than I could have ever imagined. None of this would have been possible without the work completed by prestigious researchers, and I would like to acknowledge their efforts to increase the knowledge of the public about this emerging technology.

Dedication

To the enlightened, the ones who see things differently, and want the world to be better -- they are not fond of the status quo or the existing state. You can disagree with them too much, and you can argue with them even more, but you cannot ignore them, and you cannot underestimate them, because they always change things... they push the human race forward, and while some may see them as the crazy ones or amateur, others see genius and innovators, because the ones who are enlightened enough to think that they can change the world, are the ones who do, and lead the people to the enlightenment.

Epigraph

A lab-on-a-chip (LOC) is a device that integrates one or several laboratory functions on a single integrated circuit of only millimeters to a few square centimeters to achieve automation and high-throughput screening. LOCs can handle extremely small fluid volumes down to less than pico-liters. Lab-on-a-chip devices are a subset of microelectromechanical systems (MEMS) devices and sometimes called micro total analysis systems (µTAS). LOCs may use microfluidics, the physics, manipulation and study of minute amounts of fluids. However, strictly regarded lab-on-a-chip