Palliative Care, Trials and COVID-19 Tribulations
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About this ebook
The COVID-19 pandemic started more than a year ago, but until today, we did not have a definitive cure for this disease. The SARS-CoV-2 virus constantly mutated over time, infecting more people and causing tremendous stress on the existing scarcity of healthcare resources all around the world.
Here, the experts from ground zero will share their first-hand experience of clinical trials looking for a cure for COVID-19, like the WHO's Solidarity Trial and the role of palliative care in COVID-19 as part of humanitarian crisis management.
Cheng Hoon Chew
Dr. Chew Cheng Hoon (MD, MPH) is a medical doctor working in Institute for Clinical Research with a demonstrated history of working in the hospital & health care industry. Skilled in Epidemiology, Clinical Medicine, Healthcare Information Technology (HIT), Healthcare, Healthcare Management and Health Education. Strong healthcare services professional graduated from Universiti Kebangsaan Malaysia.
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Palliative Care, Trials and COVID-19 Tribulations - Cheng Hoon Chew
Palliative Care, Trials and COVID-19 Tribulations
First-hand experience sharing from the experts at ground zero
Cheng Hoon Chew, Yan Yee Yip, Syahirah Farhana Mohd Saleh, Khairul Nisa’ Ishak, Anis Suraya Muhamad Nawawai, Chun Keat Chew, Ting Soo Chow, Richard Boon Leong Lim, Bak Leong Goh, Pik Pin Goh, Kalaiarasu M. Peariasamy
Live Webinar Series on Webinar Series on Demystifying Phases in Clinical Trials & COVID-19 Updates
Published by Institute for Clinical Research, NIH MY, 2021
Institute for Clinical Research (ICR),
National Institutes of Health, Blok B4, Aras 1, Jalan Setia Murni U13/52, Seksyen U13, Setia Alam, 40170 Shah Alam, Selangor, Malaysia
www.crc.gov.my | Phone: 603-3362 7700
Copyright © 2021 Institute for Clinical Research NIH, Malaysia
Cover and interior design by Chew Cheng Hoon.
All rights reserved.
The authors and ICR retain the sole copyright ownership of this book. Therefore, it is necessary to obtain prior permission from either the author, or the Director of Institute for Clinical Research, Ministry of Health, Malaysia, in order to reuse the content(s) of this book and/or to reproduce the content(s) of this book in any form.
PALLIATIVE CARE, TRIALS AND COVID-19 TRIBULATIONS.
First Edition, 2021.
Cite as: Cheng Hoon Chew, Yan Yee Yip, Syahirah Farhana Mohd Saleh, Khairul Nisa’ Ishak, Anis Suraya Muhamad Nawawai, Chun Keat Chew, Ting Soo Chow, Richard Boon Leong Lim, Bak Leong Goh, Pik Pin Goh, Kalaiarasu M. Peariasamy (2021) PALLIATIVE CARE, TRIALS AND COVID-19 TRIBULATIONS. Kuala Lumpur, Malaysia: Institute for Clinical Research, NIH MY.
DOI: doi.org/10.5281/zenodo.5497225
Table of Contents
Preface
Solidarity Trial - challenges and success
by Dr. Chow Ting Soo, Penang General Hospital
Introduction
What is Solidarity Trial?
Why Does it Work?
Unique Clinical Trial
The Success Part of This Trial
Streamlining the Clinical Trial Process
Clinical Trial Team
Publication
Clinical Trial Innovations
Challenges
Shipment of Investigational Product
Temperature excursion - Interferon and Hydroxychloroquine
Trial administration challenges
Standard of Care
arm
What is the Next Step?
Hope
Test, Trace, Treat, Time to Vaccinate
Reference
Palliative Care in COVID-19
by Dr Richard Lim Boon Leong, Selayang Hospital
Introduction
Definition of Palliative Care
The Role of Palliative Care in COVID-19
Who Requires Palliative Care?
Misconception of Palliative Care
What are the Main Distressing Symptoms?
Symptom Management in Severe COVID-19
Dyspnoea
Dyspnoea Management
Happy Hypoxemia
Delirium and Restlessness
Other Symptoms
Are Opioids and Sedatives Safe to Use in Severe COVID-19?
Communication
Building a Connection and Rapport in Full PPE
Phone/Video Family Conferencing
Breaking Bad News Using SPIKES
Empathy
Goals when Video Conferencing with Family Members
Reference
Q&A Session
Closing Remarks
The Panellists
Moderators
Speakers
About the Publisher
Preface
THE COVID-19 PANDEMIC started more than a year ago, but until today, we did not have a definitive cure for this disease. The SARS-CoV-2 virus constantly mutated over time, infecting more people and causing tremendous stress on the existing scarcity of healthcare resources all around the world.
Here, the experts from ground zero will share their first-hand experience of clinical trials looking for a cure for COVID-19, like the WHO's Solidarity Trial and the