Discover millions of ebooks, audiobooks, and so much more with a free trial

Only $11.99/month after trial. Cancel anytime.

Metabolic Phenotyping in Personalized and Public Healthcare
Metabolic Phenotyping in Personalized and Public Healthcare
Metabolic Phenotyping in Personalized and Public Healthcare
Ebook874 pages9 hours

Metabolic Phenotyping in Personalized and Public Healthcare

Rating: 0 out of 5 stars

()

Read preview

About this ebook

Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches.In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and its uses across personalized and population healthcare, while also covering the advent of new technology fields, such as surgical metabonomics. In addition, the text presents specific examples of where this technology has been used clinically and with efficacy, pointing towards a framework and protocol for usage as it hits the clinical mainstream.
  • Translates the conjunction of new surgical tools for intraoperative, real-time, metabolite evaluation and direct analysis of biofluid samples into novel options for augmented clinical decision-making
  • Discusses longitudinal sampling from individual patients for stratified medicine
  • Covers high resolution analytical spectroscopy and sophisticated computational modelling for prediction of adverse reactions in critical care scenarios, prognostic evaluation of cancer from biofluidism, and prognostic prediction of metabolism or response of patients to pharmaceutical interventions
  • Encapsulates recent technology options for broader population profiling considerations, in particular, the metabolome-wide association studies (MWAS) that aid the translational researcher in identifying metabolic patterns associated with disease
  • Foreword written by Professor Dame Sally Davies who is the Chief Medical Officer for England
LanguageEnglish
Release dateFeb 11, 2016
ISBN9780128004142
Metabolic Phenotyping in Personalized and Public Healthcare

Related to Metabolic Phenotyping in Personalized and Public Healthcare

Related ebooks

Biology For You

View More

Related articles

Reviews for Metabolic Phenotyping in Personalized and Public Healthcare

Rating: 0 out of 5 stars
0 ratings

0 ratings0 reviews

What did you think?

Tap to rate

Review must be at least 10 words

    Book preview

    Metabolic Phenotyping in Personalized and Public Healthcare - Jeremy Nicholson

    _book_preview_excerpt.html}nY Ej,_vtt7 $ɰ1H՗Z{)He4nWC,1cǶkrGz/ɏww_t5ٴK+qi3ɬVYO|Le4Y-i֘4閦1 ~LjӴyۙKr̳1tdef4+ҘY{.i*reҴ$eV\fyk2|laVxA!tYVEXI[MLZ6k릚5{[bLlwKTs\;nκ}ɍyQTlkL9uNժ/IaeUf7Һ߼&o@̊+VK*+"AscdY k.]Dd&&3e& @F.nՀ2oJ>֑;Nfƭw<4p<འ2o `y.4 H?/2>>M6+leVN ɛsIsu &]x,8OrPqr(eS%aW-[S\?A`+09 ZU]T떬PK.ΚKq>M|\&k  ^wtpĴ6&8 ɧ3^3yk1˳EYdxϐ l@ xuY0PMO ^)"WJ]A*dS!b֠iK! Dƥps.㳣^&rhY~RԠJok{j` a'FJGFƥBTpF?ញ*_{X?Mhi8/ t幽i*(l`~яη9=)ɯIEu-oWV!ڵmf .f%RauӾ?b6GS^X2%b I4͹ gjе ̫fj)˂þhwCcjx"X3ͮoՓ /?.@l@*zn `mv#R7NJکؖW5^@]{uW[ έV{Ht&層U^V=qSەP ;khgR\嫇R0e]WS*9X6KlEVql]KLbyI797Ukiw(0}}/i\[GϿ0D=YNݗÏT٬ 2oWtV$QϳtkkLJ5ʺjt6|\SMYeJ- áW0eɫ e>c@?2/PpQP, ,q)M:e i[6jBx׽y,'YfGggcw|7x.P`Q?hr<C&]+78ix#UG Ia`ĝX9g&oXis-lzQxp4aªD2V%K{ZЭo{XSiq͋/h;pd?y vx9 rޔ MBlZݸ;& ߼(r+'c,A?Cz vPDYo{H}{tC4/Z|H=LDAdEΎ NeT c-;c=(ϟaL\u\U=TY@-z?pKހ(xȒr;g_P9G#ܔ2M sqMCUC*d}=ht<\siJJY]S .@Ym\&Ġaݑ`HCE_PVEb;<8=uS~U'Xc 9Lnka;Ï})GĖQ.&:0w0 f<6:"{A86,_E q/ K%p4;_4vy!¾9=e#; M.XXyG&'_k(Kw̡n X 74 08^ LS5 !Oߋuj lމŲT<ֶSTټfjAUK4+5+AJ,'&4,V]:/G ĵH” RTDw3hYšr0h[_F{:mIVhV˪gX텍5e`5OoɹDCA+w~L&A "6" Aui@"g><rzosX lc I;EvA{qº\G]*Iuj >L~W:oE:gAJxI Ks[u]kyH^* E +y}lxkCg|vQeW4 LZ~ȅ`e!&_O%nO Fn}%L+&` y3Oc}"E底 7fbF6oWKh(>E[L5FL`x ?1n.E'r N4{[Ȳ| @˺}t(uQ4OxdC0{J j(1\ö[`VkGQ*p o +ȐC>CE~@n66h\T3]3H4|~{}ZE+׹i*J ;/RIp%/XrFƝڸ _DzeG5tUgk;XV"B,prbanHV)[tkzM#{+A=34Au-W V9,%LeWPjN|+pO?DEQtRv`*,ƹ'#PFB(kyL;;*@DEm$E$g{ >h+ fw8{[wq2Nң]ow6qZ{*$Mt@k):MGgk^B^T4)j}UOuL:Q`["%2ww7~ѐqEmDQ$Kr4yŚ]T C!YK,slW(>$@\{A3*Y\YpkmXb? hV,7чnhP48 Uo&Y),r)ȑ$'Plot|3Nٺ!Ӭl9™ eoO>:vCzQ~̄3:E*_d?.#;5U&4y R4JPrqW9:N;2`bh6f\m:vVFw|{?L 2MqL\a9b>$GήPpM&If!UT'v,>LN1! ?Rk b_mPbsV]\KKm2`us9sLxvy,-[t,*=O,>}euH-8UrVfl޶ v [P 7t-q .UMY$Wq|&.5@#>:+dg-`T s[𯬾xQ1*qcF~ [ӴEe r&ک- T+u V&[Vu'{֢KU !9&:VX* 5vDKh2dR>TIIQ[ǴW~3P_<\2-FTqcS̚fТ=p Z6 frvre%⭥j%{3PK[ H] `|oLZ?"`fqu+!j=Y'mJyĵ+٩]XWwV c5$Nf!*F zMҔ <}m6{YT2D}'Em~>t=/Gsn<>PP`oǞW,5&rBD+]61D_̰56?`AlAv)g BmV3 xTZ蕿068%U|63_=&ikÁc %߾||ɧ\ZѝY[oWS-;q%۱a@=Ymg\ȑXo'!= !~H#jyҔ`Ig'*iꗎN4*I,|@:!p'Q~Q*Μn럓SQ+ftʳRA0:$T?X}*&Gz 阎4Z"w,Hr!*Y䟍8dRQHN3٥p x3dinBL^1;?ZXD~ޛI2>U<([e-7V,ilǗn[b#*Il 4i662w;!CԯM{&XUş,}*W(P-p`6-:UY%ƽh A0Z(fZLizZד7lE7qgqWU]͈.~wVlaE*Z^إnʽM&ÖH-WE 258.<ֻVCpchKSDaLQZ1 j3 tkuiX3" ݥ&n!YQ^U nX9]=O'ق;Չ0 v͂%wtE˱5>1@rP{b3\2W%Y]E ;S Zj*^:zXd5$_2_H^4c ~X}5%ɷ7#͵lH$L0N&Zd=+݀F3-{nW-U&XĻ(9)Bܠp&椧RDZ+1?AJK!=h:֖$?-{yy] ^ź Oi딢Ъ1D+)d[4/ww/cռzuck[/n`FfP{osJZnET"j%jn٩!oc.Hd(ˠ5zUma/`AWV^91Gh\P>k#m\`8`ޠYs׺<>dp,Д*l f;j"ў{5 Q-}IYZ9 $k0)V`RW=<@)? ܧ;vk'ʎw9ـ&SDDӑ4#7J^)S# 'yrQ(vo n/iП2mcb {m/9p^ݷ J0,hԡ)(qOfx/y|$W&W< ]7y7F ^n2gZCJE9Q/8AC!sNXNn0s"̯a:ۂ *Xs8M~q|DQw}<- RL_`uYF^0x30NK^4%kE? SY9qOD@ 9J?ͭfK 3E6jmDQ8)}py"hQHI'M/J Un *?<(bBP 89r:' xSnN^Ul+g Bo0Jmt=66sdctg&m n~iOm /Xd3>PH5q[D/ Gt Rê PD\ňBDX*'U-qq3φ|, @_g]ΦeyinKތŷ,h`y%I!,9FNV=!_8QNfZ zžɁ=Eeѓ6ŭҨU3V8iv5= (!D;evB+E *A(,.]X^r8Af_G;{!Ѐ* \!A_K(A4eG,Lb;lBK=?rސk͢=Xa}9J1oc{fTq}-B?FcԂiߟfO,Gި3Wt&Ѭd'{&Iw 6`(*?ޯ3Ҙ0;4?BIMZkmO m= ~i&bl^)]&ZIZJ [tu ~[{& /Z+- A,Lnddclqu(_=O];|i(I}MpXW-kL+q' wn|C>DаfAAuZ0ŶXU 6D&wfn7e%dSm&|z¿lY%BWApq@?2lg:jӳvD^ q fc)ah9EVv%.):Gq0V)?M+5p&nty-u7u'/lc8RTFMM#*H8MgIyڌg_ml)X9P 8 Z Lb(d1`Bz),]-_-QJt_i]'Sط/w ޵ ) ̀qt^4ºR8rlJjա0n+j^,5F81iך_ݭ]e#5& w z BaDƦK"+Ӹ6+}qԵupT[бe[8p.GhlUKÑ\тLK&_ \s"eJI`ƪ* _%^^{ն Eʸq«z htC# ?#.CWP Mv.Z>>Kv'EDpLI]\'UGE-xB89b0dX^Znn4R)@ʮriQǁZ#`P24؛8 Y[; Zyjv} Kf4OksΜQ1̓"[&D(T󼰃D(*:XQEtE}89 L6O;us#~ #eŧt R4u.A+cw|%鰜J$/l`UZT&*K/7fѶ /Wgl1+v/睵ԾM&ls㠨Қ .z#) g~ۇgS۾hUl.:Ni4:KC….{}̉k֖ceɜBBJdY=ᐵS{]<#(>6~!x sp\VE>̭R=0RCn (4uׇ3ߕ(rx]fʩҴt}^l MSQ45FUd$vx N!^wcB_|MG%C%1dJcved-V#GREm==鸲#I_a''i)?+)épbsVja 2H݅]Fqys$'Vnd/MQ[Ή^ڞ }÷maX&o^ǃ'LzO8~.-zJf'6Yܨy+C8_˼{GQ]#>'U P8O0׿~9(g2įk_.F{vto%W5?=٪d `} ï }}zv۳)gݲ_Hm3aRG''{O/\'U8L~y~0z/ir3<|}|'_>L2=4K].!dbYI5ݿ,K;>3)Y_Qze M~;|hQj"$-,P.HnJ#+׿}%櫬+ى(}=ɯv|y6<4}=;\SeɦH.cA|UA#R%ޤۺOK}M*M˷Puu>3`[ߗ`qg &.ڶu#+I\\RM2$d<}.$6@`pt̠'xl</imQB/b[6:q $q|vwq:OhFAq`^9|HK~~_s f;|lhȓdwқ{<>?ٻ8]wqLtFЯ;p߹rc[GQ/sʊƛ?FNuFS&GZr5L{gspe,j *_"SN4le{)C0%[-sl9͔lh"|Q䨒m+s9d[RqdR͋Ђ@F$1Y 51>U5*98f#ઔjGq)`x|A||r̯92٢0O 5ieJަx 7~b?<%[;Ms:'ߑmq~n~ >=#ˌGbFj|M̂潚e+u?_-EnwS;vUo*Գ|
    Enjoying the preview?
    Page 1 of 1