ABC Transporters and Multidrug Resistance
()
About this ebook
ATP-binding cassette transporter genes (ABC transporters) are known to play a crucial role in the development of multidrug resistance (MDR). MDR is the ability of pathologic cells, such as tumors, to withstand chemicals designed to target and destroy such cells. In MDR, patients who are on medication eventually develop resistance to not only the drug they are taking, but to several different types of drugs.
ABC Transporters and Multidrug Resistance offers an essential resource for pharmaceutical researchers who are working to discover drugs to counteract multidrug resistance in diseases such as cancer. In one comprehensive volume, this book contains a collection of the most current knowledge on the involvement of ABC transporters in drug transport and resistance.
This comprehensive volume provides an overview on the description of the structure, the genome, normal tissue expression, physiological aspect, and mechanism of action of the ABC protein. The expert contributors explore the expression, detection, and implications of ABC proteins in hematological malignancies and solid tumors and ABC proteins and pathogenic microorganisms. This volume also explains MDR modulation through inhibition of ABC transporters and the design of inhibitors and mechanism of action. In addition, the book offers essential information on the biological and clinical aspect of multidrug resistance.
Related to ABC Transporters and Multidrug Resistance
Titles in the series (14)
Glycogen Synthase Kinase 3 (GSK-3) and Its Inhibitors: Drug Discovery and Development Rating: 0 out of 5 stars0 ratingsAminoglycoside Antibiotics: From Chemical Biology to Drug Discovery Rating: 0 out of 5 stars0 ratingsKinase Inhibitor Drugs Rating: 0 out of 5 stars0 ratingsCarbohydrate-Based Vaccines and Immunotherapies Rating: 0 out of 5 stars0 ratingsHIV-1 Integrase: Mechanism and Inhibitor Design Rating: 0 out of 5 stars0 ratingsABC Transporters and Multidrug Resistance Rating: 0 out of 5 stars0 ratingsEvaluation of Drug Candidates for Preclinical Development: Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology Rating: 0 out of 5 stars0 ratingsOral Bioavailability: Basic Principles, Advanced Concepts, and Applications Rating: 0 out of 5 stars0 ratingsDendrimer-Based Drug Delivery Systems: From Theory to Practice Rating: 0 out of 5 stars0 ratingsPlant Bioactives and Drug Discovery: Principles, Practice, and Perspectives Rating: 0 out of 5 stars0 ratingsCarbohydrate Recognition: Biological Problems, Methods, and Applications Rating: 0 out of 5 stars0 ratingsDrug Delivery: Principles and Applications Rating: 0 out of 5 stars0 ratingsCyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery Rating: 0 out of 5 stars0 ratingsDrug Transporters: Molecular Characterization and Role in Drug Disposition Rating: 0 out of 5 stars0 ratings
Related ebooks
Drug Resistance As a Biochemical Target in Cancer Chemotherapy Rating: 0 out of 5 stars0 ratingsOncogenomics: Molecular Approaches to Cancer Rating: 0 out of 5 stars0 ratingsCancer Vaccines and Tumor Immunity Rating: 0 out of 5 stars0 ratingsAdvances in Immunopharmacology: Proceedings of the Second International Conference on Immunopharmacology, July 1982, Washington, USA Rating: 0 out of 5 stars0 ratingsEnzyme Inhibition in Drug Discovery and Development: The Good and the Bad Rating: 0 out of 5 stars0 ratingsDrug Efficacy, Safety, and Biologics Discovery: Emerging Technologies and Tools Rating: 0 out of 5 stars0 ratingsAccelerated Path to Cures Rating: 0 out of 5 stars0 ratingsMolecular Pathology in Clinical Practice Rating: 0 out of 5 stars0 ratingsTargeting Protein Kinases for Cancer Therapy Rating: 0 out of 5 stars0 ratingsBiotechnology and Food Safety: Proceedings of the Second International Symposium Rating: 5 out of 5 stars5/5Mechanisms of Drug Resistance in Neoplastic Cells: Bristol-Myers Cancer Symposia, Vol. 9 Rating: 0 out of 5 stars0 ratingsViral Oncology: Basic Science and Clinical Applications Rating: 0 out of 5 stars0 ratingsMicrobial Proteomics: Functional Biology of Whole Organisms Rating: 0 out of 5 stars0 ratingsProtein Instability at Interfaces During Drug Product Development: Fundamental Understanding, Evaluation, and Mitigation Rating: 0 out of 5 stars0 ratingsPreharvest and Postharvest Food Safety: Contemporary Issues and Future Directions Rating: 0 out of 5 stars0 ratingsClinical and Experimental Toxicology of Organophosphates and Carbamates Rating: 0 out of 5 stars0 ratingsIntercellular Signaling in Development and Disease: Cell Signaling Collection Rating: 0 out of 5 stars0 ratingsAACR 2022 Proceedings: Part A Online-Only and April 10 Rating: 0 out of 5 stars0 ratingsImmunity to Cancer Rating: 0 out of 5 stars0 ratingsPrecision Molecular Pathology of Prostate Cancer Rating: 0 out of 5 stars0 ratingsThe Microbiological Safety of Food in Healthcare Settings Rating: 0 out of 5 stars0 ratingsMacrophage Regulation of Immunity Rating: 0 out of 5 stars0 ratingsDevelopmental Aspects of Carcinogenesis and Immunity Rating: 0 out of 5 stars0 ratingsCarbohydrate-Based Vaccines and Immunotherapies Rating: 0 out of 5 stars0 ratingsMolecular Mechanisms and Their Clinical Application in Malignancies Rating: 0 out of 5 stars0 ratingsGene Therapy for Viral Infections Rating: 5 out of 5 stars5/5Novel Approaches to Cancer Chemotherapy Rating: 0 out of 5 stars0 ratingsTransduction Mechanisms in Cellular Signaling: Cell Signaling Collection Rating: 0 out of 5 stars0 ratingsNonclinical Development of Novel Biologics, Biosimilars, Vaccines and Specialty Biologics Rating: 0 out of 5 stars0 ratings
Medical For You
The Lost Book of Simple Herbal Remedies: Discover over 100 herbal Medicine for all kinds of Ailment Inspired By Barbara O'Neill Rating: 0 out of 5 stars0 ratingsThe 40 Day Dopamine Fast Rating: 4 out of 5 stars4/5The Vagina Bible: The Vulva and the Vagina: Separating the Myth from the Medicine Rating: 5 out of 5 stars5/5Holistic Herbal: A Safe and Practical Guide to Making and Using Herbal Remedies Rating: 4 out of 5 stars4/5Mediterranean Diet Meal Prep Cookbook: Easy And Healthy Recipes You Can Meal Prep For The Week Rating: 5 out of 5 stars5/5Rewire Your Brain: Think Your Way to a Better Life Rating: 4 out of 5 stars4/5The Hormone Reset Diet: Heal Your Metabolism to Lose Up to 15 Pounds in 21 Days Rating: 4 out of 5 stars4/5Period Power: Harness Your Hormones and Get Your Cycle Working For You Rating: 4 out of 5 stars4/5Adult ADHD: How to Succeed as a Hunter in a Farmer's World Rating: 4 out of 5 stars4/5Tight Hip Twisted Core: The Key To Unresolved Pain Rating: 4 out of 5 stars4/5What Happened to You?: Conversations on Trauma, Resilience, and Healing Rating: 4 out of 5 stars4/5ATOMIC HABITS:: How to Disagree With Your Brain so You Can Break Bad Habits and End Negative Thinking Rating: 5 out of 5 stars5/5The Diabetes Code: Prevent and Reverse Type 2 Diabetes Naturally Rating: 4 out of 5 stars4/5Herbal Healing for Women Rating: 4 out of 5 stars4/5Gut: The Inside Story of Our Body's Most Underrated Organ (Revised Edition) Rating: 4 out of 5 stars4/5The Amazing Liver and Gallbladder Flush Rating: 5 out of 5 stars5/5Woman: An Intimate Geography Rating: 4 out of 5 stars4/5Living Daily With Adult ADD or ADHD: 365 Tips o the Day Rating: 5 out of 5 stars5/5The Art of Dying Well: A Practical Guide to a Good End of Life Rating: 4 out of 5 stars4/5Women With Attention Deficit Disorder: Embrace Your Differences and Transform Your Life Rating: 5 out of 5 stars5/5Working Stiff: Two Years, 262 Bodies, and the Making of a Medical Examiner Rating: 4 out of 5 stars4/5Healthy Gut, Healthy You: The Personalized Plan to Transform Your Health from the Inside Out Rating: 4 out of 5 stars4/5The Song of the Cell: An Exploration of Medicine and the New Human Rating: 4 out of 5 stars4/5The Butchering Art: Joseph Lister's Quest to Transform the Grisly World of Victorian Medicine Rating: 4 out of 5 stars4/5
Reviews for ABC Transporters and Multidrug Resistance
0 ratings0 reviews