The Ageless Brain: How to Sharpen and Protect Your Mind for a Lifetime

Written by Dale E. Bredesen, MD

Narrated by Robert Petkoff

“Narrator Robert Petkoff strikes a perfect balance between an authoritative tone and a warm and friendly approach.”—AudioFile

From the bestselling author of The End of Alzheimer’s, Dr. Dale Bredesen, comes a revolutionary new approach to preventing the onset of neurodegenerative disease and creating sustained brain health.

In recent decades, advances in medicine have changed the way we think about our health. Chronic diseases like obesity, heart disease, and diabetes can be prevented or reversed. Cancer treatment has become targeted and personalized. Gene editing will allow us to eradicate many inherited disorders. But there is one class of conditions that continues to elude researchers and cause tremendous suffering: neurodegenerative disease.

More than six million Americans live with Alzheimer’s disease; by 2050, this number is projected to reach thirteen million. An additional one in ten people over the age of sixty-five have dementia, while 22 percent of older adults live with some form of cognitive impairment. And it isn’t just the elderly who are afflicted; diagnosis rates are rising in younger adults, with women at a higher risk than men. For many—especially those with a genetic predisposition—this fate has seemed inevitable. Until now.

Dr. Dale Bredesen is a pioneer in the field of neurodegenerative research. Lauded for his integrative protocol, he has, in clinical studies, reversed the symptoms of Alzheimer’s and dementia. He shared this information in his bestselling book, The End of Alzheimer’s. But Dr. Bredesen doesn’t want to only treat the symptoms of this devastating illness. He wants to prevent it from developing in the first place.

In The Ageless Brain, Dr. Bredesen will share the latest, cutting-edge science on neurodegeneration, including how misunderstandings of the disease have hindered our efforts to treat it, as well as a preventative program that listeners of all ages can put into practice to optimize their cognitive health now and sustain it for years to come. This is an audiobook for everyone who cares about their ability to stay sharp and independent for a lifetime, for those who have witnessed family members decline, and for the many listeners who are beginning to experience moments of brain fog or fatigue in middle age, and are concerned about what the future may hold.

Just as bestselling authors like Dr. Peter Attia and Dr. Michael Greger have offered essential guidance for maintaining overall health and longevity, Dr. Bredesen has written the only book you need to retain your vibrant mind—and thrive for a lifetime.

A Macmillan Audio production from Flatiron Books.

• Language: English
• Publisher: Macmillan Audio
• Release date: Mar 25, 2025
• ISBN: 9781250381439

Dale E. Bredesen, MD

Dale Bredesen, M.D., is internationally recognized as an expert in the mechanisms of neurodegenerative diseases such as Alzheimer’s disease. He graduated from Caltech, then earned his M.D. from Duke University Medical Center in Durham, North Carolina. He served as chief resident in neurology at the University of California, San Francisco (UCSF) before joining Nobel laureate Stanley Prusiner’s laboratory at UCSF as an NIH postdoctoral fellow. He held faculty positions at UCSF, UCLA, and the University of California, San Diego. Dr. Bredesen directed the Program on Aging at the Burnham Institute before coming to the Buck Institute in 1998 as its founding president and CEO. He is the chief medical officer of MPI Cognition.