India Today

THE WONDER DRUG

Nitin Chaddha (name changed), a 44-year-old businessman in Delhi, gained 23 kilos during the Covid pandemic. It affected not just his marital relationship, but also his self-esteem. “I couldn’t bear to look at myself in the mirror, or have my pictures taken,” he says. Then, he approached the doctor who had been treating his brother for diabetes. His brother is taking Rybelsus, the oral version of Ozempic, both of which contain a revolutionary ingredient called semaglutide, which while helping regulate sugar, also results in weight loss. “My brother lost seven kilos in a few months,” says Chaddha, who is not diabetic but is morbidly obese, with a BMI of 34. “I met his doctor and, under his guidance, used the drug to lose 10 kilos myself.” He has been on Rybelsus for four months now.

It is being hailed as the new miracle medication. The reason semaglutide caught everyone’s fancy was in its dual benefit—not only does it aid insulin production, it also helps the body lose 10-15 per cent of its weight by curbing hunger and promoting a feeling of satiety. Danish pharma giant Novo Nordisk presented, in three avatars, the injectable Ozempic, its oral version Rybelsus (both approved for treatment of diabetes) and Wegovy, an injectable approved specifically for weight loss. “It suited me so well,” says 48-year-old Anuradha Verma (name changed), the wife of a Mumbai-based businessman, who has been spending her “shopping allowance” to go to Dubai every two weeks since June 2023 to source Ozempic. Diagnosed with diabetes four years ago, the drug has been a life-saver for Verma. “Not only is my blood sugar under control, I have also shed eight kilos since I began taking it,” she says. On March 8, the US Food and Drug Administration (FDA) approved Wegovy for treating adults with cardiovascular disease (CVD) as well.

hat can only be good news in a country that is the diabetes capital of the world, and which, along with the US and China, was found to be among the countries with “the largest absolute numbers of adults with obesity in 2022”, and whose population is also susceptible to early onset of heart disease. The Indian Council of Medical Research and the India Diabetes (ICMR-INDIAB) Study published in 2023 estimated 101 million people in India to be suffering from diabetes in 2021 and another 136of Public Health in 2014 estimated that the economic losses India would suffer on account of CVD between 2012 and 2030 would be approximately $2.17 trillion (Rs 180 lakh crore, in today’s terms).

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