Chicago Tribune

Revolutionary gene therapy may offer new life for patients battling chronic sickle cell disease

Lyric Porter, right, receives an injection of medication from nurse Lexie Egan during at the University of Chicago's Comer Children's Hospital on Dec. 20, 2023.

Lyric Porter wanted her life back. Born with sickle cell disease, she had a fever at age 5 that scarred her lungs and required her to roll an oxygen tank to school. When she was growing up, clogged blood vessels racked her body with stabbing sensations and forced her to be hospitalized again and again.

When she learned of a new experimental treatment at the University of Chicago Medicine to alter her genes and possibly cure her, she decided to take it. The process itself was an ordeal, but more than a year later, at age 27, Porter is feeling better, has more energy and has stayed out of the hospital.

“I had to take

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