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Antibiotics that fight deadly infections in babies are losing their power

New research finds that the most commonly prescribed antibiotics in Southeast Asia are only 50% effective at treating sepsis and meningitis in newborns. It's a cause for global concern.
The above illustration depicts a molecular model for a carbapenem drug. The carbapenem group of antibiotics is the last resort for antibiotic-resistant infections and is approved for children. But carbapenems are not widely used because they're expensive, they're administered by IV — and doctors are concerned that bacteria could develop resistance to these antibiotics.

The drugs aren't working as well as they used to.

That's the sobering takeaway from new research published in The Lancet Regional Health – Southeast Asia last week: The most commonly prescribed antibiotics in Southeast Asia are now only 50% effective at treating sepsis and meningitis in newborns.

And that's a serious setback. Sepsis kills 1 in 5 patients. Meningitis is responsible for a quarter of million deaths a year – half among children under the age of 5. Overall, childhood infections are responsible for over 550,000 deaths each year.

Why aren't the drugs doing their job? It's because overuse of those

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