BBC Science Focus Magazine

AN END TO AGEING?

Picture the scene. After a routine blood test, you visit your GP for the results. “It’s all good,” says the doctor reassuringly. “The only problem is that you’re getting older.” Then, with a flourish of the prescription pad, the doctor adds: “But I can help you with that. Take these tablets. They’ll slow the ageing process and help you to stay healthy. Oh, and they might just make you live longer too.”

A drug that extends your life, slows ageing and staves off the ravages of old age, including frailty and disease? It sounds too good to be true, and yet, an increasing weight of evidence suggests not just that these drugs are within reach, but that they may already be here. Some can be found on the shelves at your local health store, while others are drugs for conditions such as diabetes and cancer that are being repurposed. Animal studies have demonstrated their potential, and now clinical trials are beginning to assess if their promise holds true in humans. If it does, those who are middle-aged now could become the first generation to benefit from their use. Imagine an 80-year-old with the biology and ‘get up and go’ of someone 30 years younger. How joyful not to have to act your

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