Joe Biden, on the ropes, looks for first win as 2020 campaign moves to South Carolina

CHARLESTON, S.C. - Former Vice President Joe Biden, leaving Las Vegas behind, is placing all his chips on South Carolina as his best - and perhaps last - chance to reverse a string of losses in early-voting states and mount a serious challenge to Sen. Bernie Sanders for the Democratic nomination.

As the Democratic contest moves here, the electorate for the first time this primary season will feature an African American majority, testing support for the candidates among a key segment of the Democratic base. Saturday's primary also marks the final single-state contest before the race dramatically widens to 14 states, including California, which vote on March 3, Super Tuesday.

If Biden doesn't clean up here, where he has longstanding personal and political ties, the result could wipe out the remaining hope for the candidate once considered the front-runner