NPR

Scientists Release Controversial Genetically Modified Mosquitoes In High-Security Lab

The insects were created, using CRISPR, to carry a powerful "gene drive." The mosquitoes could provide a potent weapon against malaria, but they raise fears about unpredictable environmental effects.
Genetically modified "gene drive" mosquitoes feed on warm cow's blood. Scientists hope these mosquitoes could help eradicate malaria.

Scientists have launched a major new phase in the testing of a controversial genetically modified organism: a mosquito designed to quickly spread a genetic mutation lethal to its own species, NPR has learned.

For the first time, researchers have begun large-scale releases of the engineered insects, into a high-security laboratory in Terni, Italy.

"This will really be a breakthrough experiment," says Ruth Mueller, an entomologist who runs the lab. "It's a historic moment."

The goal is to see if the mosquitoes could eventually provide a powerful new weapon to help eradicate malaria in Africa, where most cases occur.

"It's very exciting," Mueller says.

NPR was the only news organization allowed into the lab to witness the moment the releases began in early February.

The lab was specially built to evaluate the modified insects in as close to a natural environment as possible without the risk of releasing them into the wild, about which there are deep concerns regarding unforeseen effects on the environment.

"This is an experimental technology which couldof Friends of the Earth, an environmental group that's part of an international coalition fighting this new generation of modified organisms.

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